Bock LV - Search Results

1

Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88.

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmüller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R. Lauer SM, et al. Among authors: bock lv. Nat Commun. 2024 May 10;15(1):3945. doi: 10.1038/s41467-024-48027-4. Nat Commun. 2024. PMID: 38730238 Free PMC article.

2

Effects of cryo-EM cooling on structural ensembles.

Bock LV, Grubmüller H. Bock LV, et al. Nat Commun. 2022 Mar 31;13(1):1709. doi: 10.1038/s41467-022-29332-2. Nat Commun. 2022. PMID: 35361752 Free PMC article.

3

Energy barriers and driving forces in tRNA translocation through the ribosome.

Bock LV, Blau C, Schröder GF, Davydov II, Fischer N, Stark H, Rodnina MV, Vaiana AC, Grubmüller H. Bock LV, et al. Nat Struct Mol Biol. 2013 Dec;20(12):1390-6. doi: 10.1038/nsmb.2690. Epub 2013 Nov 3. Nat Struct Mol Biol. 2013. PMID: 24186064

4

A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.

Arenz S, Bock LV, Graf M, Innis CA, Beckmann R, Grubmüller H, Vaiana AC, Wilson DN. Arenz S, et al. Among authors: bock lv. Nat Commun. 2016 Jul 6;7:12026. doi: 10.1038/ncomms12026. Nat Commun. 2016. PMID: 27380950 Free PMC article.

5

Molecular simulations of the ribosome and associated translation factors.

Bock LV, Kolář MH, Grubmüller H. Bock LV, et al. Curr Opin Struct Biol. 2018 Apr;49:27-35. doi: 10.1016/j.sbi.2017.11.003. Epub 2017 Dec 1. Curr Opin Struct Biol. 2018. PMID: 29202442 Free article. Review.

6

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics.

Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmüller H, Mankin AS, Innis CA, Vázquez-Laslop N, Wilson DN. Beckert B, et al. Among authors: bock lv. Nat Commun. 2021 Jul 22;12(1):4466. doi: 10.1038/s41467-021-24674-9. Nat Commun. 2021. PMID: 34294725 Free PMC article.

7

Simulation of Complex Biomolecular Systems: The Ribosome Challenge.

Bock LV, Gabrielli S, Kolář MH, Grubmüller H. Bock LV, et al. Annu Rev Biophys. 2023 May 9;52:361-390. doi: 10.1146/annurev-biophys-111622-091147. Epub 2023 Jan 31. Annu Rev Biophys. 2023. PMID: 36719969 Free article. Review.

8

Structural conservation of antibiotic interaction with ribosomes.

Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO, Morici M, Beckert B, Myasnikov AG, Grubmüller H, Nováček J, Wilson DN. Paternoga H, et al. Among authors: bock lv. Nat Struct Mol Biol. 2023 Sep;30(9):1380-1392. doi: 10.1038/s41594-023-01047-y. Epub 2023 Aug 7. Nat Struct Mol Biol. 2023. PMID: 37550453 Free PMC article.

9

RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.

Morici M, Gabrielli S, Fujiwara K, Paternoga H, Beckert B, Bock LV, Chiba S, Wilson DN. Morici M, et al. Among authors: bock lv. Nat Commun. 2024 Mar 19;15(1):2432. doi: 10.1038/s41467-024-46761-3. Nat Commun. 2024. PMID: 38503735 Free PMC article.

10

The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome.

Gersteuer F, Morici M, Gabrielli S, Fujiwara K, Safdari HA, Paternoga H, Bock LV, Chiba S, Wilson DN. Gersteuer F, et al. Among authors: bock lv. Nat Commun. 2024 Mar 19;15(1):2431. doi: 10.1038/s41467-024-46762-2. Nat Commun. 2024. PMID: 38503753 Free PMC article.

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