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A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.
Sabarwal A, van Rooyen JC, Caburet J, Avgenikos M, Dheeraj A, Ali M, Mishra D, de Meester JSB, Stander S, van Otterlo WAL, Kaschula CH, Singh RP. Sabarwal A, et al. Among authors: dheeraj a. FASEB J. 2022 Dec;36(12):e22654. doi: 10.1096/fj.202200669RR. FASEB J. 2022. PMID: 36421014
Reengineering Ponatinib to Minimize Cardiovascular Toxicity.
Hnatiuk AP, Bruyneel AAN, Tailor D, Pandrala M, Dheeraj A, Li W, Serrano R, Feyen DAM, Vu MM, Amatya P, Gupta S, Nakauchi Y, Morgado I, Wiebking V, Liao R, Porteus MH, Majeti R, Malhotra SV, Mercola M. Hnatiuk AP, et al. Among authors: dheeraj a. Cancer Res. 2022 Aug 3;82(15):2777-2791. doi: 10.1158/0008-5472.CAN-21-3652. Cancer Res. 2022. PMID: 35763671 Free PMC article.
Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide-Based Hybrid Compounds against SARS-CoV-2 and Cancer.
Herrmann L, Yaremenko IA, Çapcı A, Struwe J, Tailor D, Dheeraj A, Hodek J, Belyakova YY, Radulov PS, Weber J, Malhotra SV, Terent'ev AO, Ackermann L, Tsogoeva SB. Herrmann L, et al. Among authors: dheeraj a. ChemMedChem. 2022 May 4;17(9):e202200005. doi: 10.1002/cmdc.202200005. Epub 2022 Mar 29. ChemMedChem. 2022. PMID: 35187791 Free PMC article.
Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor D, Going CC, Resendez A, Kumar V, Nambiar DK, Li Y, Dheeraj A, LaGory EL, Ghoochani A, Birk AM, Stoyanova T, Ye J, Giaccia AJ, Le QT, Singh RP, Sledge GW, Pitteri SJ, Malhotra SV. Tailor D, et al. Among authors: dheeraj a. Br J Cancer. 2021 Feb;124(3):604-615. doi: 10.1038/s41416-020-01137-4. Epub 2020 Nov 3. Br J Cancer. 2021. PMID: 33139797 Free PMC article.
13 results