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Page 1
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain.
Gulej R, Nyúl-Tóth Á, Csik B, Patai R, Petersen B, Negri S, Chandragiri SS, Shanmugarama S, Mukli P, Yabluchanskiy A, Conley S, Huffman D, Tarantini S, Csiszar A, Ungvari Z. Gulej R, et al. Among authors: shanmugarama s. Geroscience. 2024 Oct;46(5):4415-4442. doi: 10.1007/s11357-024-01154-8. Epub 2024 May 10. Geroscience. 2024. PMID: 38727872 Free PMC article.
Endothelial deficiency of insulin-like growth factor-1 receptor leads to blood-brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype.
Gulej R, Csik B, Faakye J, Tarantini S, Shanmugarama S, Chandragiri SS, Mukli P, Conley S, Csiszar A, Ungvari Z, Yabluchanskiy A, Nyúl-Tóth Á. Gulej R, et al. Among authors: shanmugarama s. Microcirculation. 2024 Feb;31(2):e12840. doi: 10.1111/micc.12840. Epub 2023 Dec 11. Microcirculation. 2024. PMID: 38082450
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax.
Faakye J, Nyúl-Tóth Á, Muranyi M, Gulej R, Csik B, Shanmugarama S, Tarantini S, Negri S, Prodan C, Mukli P, Yabluchanskiy A, Conley S, Toth P, Csiszar A, Ungvari Z. Faakye J, et al. Among authors: shanmugarama s. Geroscience. 2024 Feb;46(1):21-37. doi: 10.1007/s11357-023-01024-9. Epub 2023 Dec 4. Geroscience. 2024. PMID: 38044400 Free PMC article.
Imaging the time course, morphology, neuronal tissue compression, and resolution of cerebral microhemorrhages in mice using intravital two-photon microscopy: insights into arteriolar, capillary, and venular origin.
Faakye J, Nyúl-Tóth Á, Gulej R, Csik B, Tarantini S, Shanmugarama S, Prodan C, Mukli P, Yabluchanskiy A, Conley S, Toth P, Csiszar A, Ungvari Z. Faakye J, et al. Among authors: shanmugarama s. Geroscience. 2023 Oct;45(5):2851-2872. doi: 10.1007/s11357-023-00839-w. Epub 2023 Jun 20. Geroscience. 2023. PMID: 37338779 Free PMC article.
Drug delivery approaches for HuR-targeted therapy for lung cancer.
Raguraman R, Shanmugarama S, Mehta M, Elle Peterson J, Zhao YD, Munshi A, Ramesh R. Raguraman R, et al. Among authors: shanmugarama s. Adv Drug Deliv Rev. 2022 Jan;180:114068. doi: 10.1016/j.addr.2021.114068. Epub 2021 Nov 22. Adv Drug Deliv Rev. 2022. PMID: 34822926 Free PMC article. Review.