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Page 1
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide.
Russo M, Gualdrini F, Vallelonga V, Prosperini E, Noberini R, Pedretti S, Borriero C, Di Chiaro P, Polletti S, Imperato G, Marenda M, Ghirardi C, Bedin F, Cuomo A, Rodighiero S, Bonaldi T, Mitro N, Ghisletti S, Natoli G. Russo M, et al. Among authors: polletti s. Mol Cell. 2024 Mar 7;84(5):967-980.e10. doi: 10.1016/j.molcel.2023.12.033. Epub 2024 Jan 18. Mol Cell. 2024. PMID: 38242130
A first exon termination checkpoint preferentially suppresses extragenic transcription.
Austenaa LMI, Piccolo V, Russo M, Prosperini E, Polletti S, Polizzese D, Ghisletti S, Barozzi I, Diaferia GR, Natoli G. Austenaa LMI, et al. Among authors: polletti s. Nat Struct Mol Biol. 2021 Apr;28(4):337-346. doi: 10.1038/s41594-021-00572-y. Epub 2021 Mar 25. Nat Struct Mol Biol. 2021. PMID: 33767452 Free PMC article.
Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription.
Russo M, Piccolo V, Polizzese D, Prosperini E, Borriero C, Polletti S, Bedin F, Marenda M, Michieletto D, Mandana GM, Rodighiero S, Cuomo A, Natoli G. Russo M, et al. Among authors: polletti s. Genes Dev. 2023 Dec 26;37(21-24):1017-1040. doi: 10.1101/gad.351057.123. Genes Dev. 2023. PMID: 38092518 Free PMC article.
Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer.
Di Chiaro P, Nacci L, Arco F, Brandini S, Polletti S, Palamidessi A, Donati B, Soriani C, Gualdrini F, Frigè G, Mazzarella L, Ciarrocchi A, Zerbi A, Spaggiari P, Scita G, Rodighiero S, Barozzi I, Diaferia GR, Natoli G. Di Chiaro P, et al. Among authors: polletti s. Cancer Cell. 2024 Apr 8;42(4):662-681.e10. doi: 10.1016/j.ccell.2024.02.017. Epub 2024 Mar 21. Cancer Cell. 2024. PMID: 38518775
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer.
Cortesi A, Gandolfi F, Arco F, Di Chiaro P, Valli E, Polletti S, Noberini R, Gualdrini F, Attanasio S, Citron F, Ho IL, Shah R, Yen EY, Spinella MC, Ronzoni S, Rodighiero S, Mitro N, Bonaldi T, Ghisletti S, Monticelli S, Viale A, Diaferia GR, Natoli G. Cortesi A, et al. Among authors: polletti s. Sci Adv. 2024 Mar 29;10(13):eadk5386. doi: 10.1126/sciadv.adk5386. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536927 Free PMC article.
26 results