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Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function.
Karyu H, Niki T, Sorimachi Y, Hata S, Shimabukuro-Demoto S, Hirabayashi T, Mukai K, Kasahara K, Takubo K, Goda N, Honke K, Taguchi T, Sorimachi H, Toyama-Sorimachi N. Karyu H, et al. Among authors: taguchi t. Front Immunol. 2024 Apr 24;15:1401294. doi: 10.3389/fimmu.2024.1401294. eCollection 2024. Front Immunol. 2024. PMID: 38720899 Free PMC article.
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
Uchida Y, Hasegawa J, Chinnapen D, Inoue T, Okazaki S, Kato R, Wakatsuki S, Misaki R, Koike M, Uchiyama Y, Iemura S, Natsume T, Kuwahara R, Nakagawa T, Nishikawa K, Mukai K, Miyoshi E, Taniguchi N, Sheff D, Lencer WI, Taguchi T, Arai H. Uchida Y, et al. Among authors: taguchi t. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15846-51. doi: 10.1073/pnas.1109101108. Epub 2011 Sep 12. Proc Natl Acad Sci U S A. 2011. PMID: 21911378 Free PMC article.
Activation of STING requires palmitoylation at the Golgi.
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T. Mukai K, et al. Among authors: taguchi t. Nat Commun. 2016 Jun 21;7:11932. doi: 10.1038/ncomms11932. Nat Commun. 2016. PMID: 27324217 Free PMC article.
STING palmitoylation as a therapeutic target.
Hansen AL, Mukai K, Schopfer FJ, Taguchi T, Holm CK. Hansen AL, et al. Among authors: taguchi t. Cell Mol Immunol. 2019 Mar;16(3):236-241. doi: 10.1038/s41423-019-0205-5. Epub 2019 Feb 22. Cell Mol Immunol. 2019. PMID: 30796349 Free PMC article. Review.
Innate immunity signalling and membrane trafficking.
Taguchi T, Mukai K. Taguchi T, et al. Curr Opin Cell Biol. 2019 Aug;59:1-7. doi: 10.1016/j.ceb.2019.02.002. Epub 2019 Mar 12. Curr Opin Cell Biol. 2019. PMID: 30875551 Free article. Review.
FAM48A mediates compensatory autophagy induced by proteasome impairment.
Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S. Arata Y, et al. Among authors: taguchi t. Genes Cells. 2019 Aug;24(8):559-568. doi: 10.1111/gtc.12708. Epub 2019 Jul 3. Genes Cells. 2019. PMID: 31210371 Free article.
2,977 results