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Kaempferol-3-O-α-(3,4-di-E-p-coumaroyl)-rhamnopyranoside from Nectandra oppositifolia releases Ca2+ from intracellular pools of Trypanosoma cruzi affecting the bioenergetics system.
Conserva GA, Costa-Silva TA, Quirós-Guerrero LM, Marcourt L, Wolfender JL, Queiroz EF, Tempone AG, Lago JHG. Conserva GA, et al. Among authors: lago jhg. Chem Biol Interact. 2021 Nov 1;349:109661. doi: 10.1016/j.cbi.2021.109661. Epub 2021 Sep 16. Chem Biol Interact. 2021. PMID: 34537181 Free article.
New derivatives from dehydrodieugenol B and its methyl ether displayed high anti-Trypanosoma cruzi activity and cause depolarization of the plasma membrane and collapse the mitochondrial membrane potential.
Galhardo TS, Ueno AK, Costa-Silva TA, Tempone AG, Carvalho WA, Fischmeister C, Bruneau C, Mandelli D, Lago JHG. Galhardo TS, et al. Among authors: lago jhg. Chem Biol Interact. 2022 Oct 1;366:110129. doi: 10.1016/j.cbi.2022.110129. Epub 2022 Sep 5. Chem Biol Interact. 2022. PMID: 36067825 Free article.
223 results