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A 13.2 mg epinephrine intranasal spray demonstrates comparable pharmacokinetics, pharmacodynamics, and safety to a 0.3 mg epinephrine autoinjector.
Dworaczyk DA, Hunt AL, Di Spirito M, Lor M, Dretchen KL, Lamson MJ, Pollock J, Ward T. Dworaczyk DA, et al. Among authors: hunt al. J Allergy Clin Immunol Glob. 2023 Dec 12;3(2):100200. doi: 10.1016/j.jacig.2023.100200. eCollection 2024 May. J Allergy Clin Immunol Glob. 2023. PMID: 38328805 Free PMC article.
Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial.
Xu G, Paglialunga S, Qian X, Ding R, Webster K, van Haarst A, Engel C, Hui CW, Lam LH, Li W, Wu WC, Rasmussen S, Hunt A, Leung SO. Xu G, et al. Among authors: hunt a. Front Immunol. 2024 Dec 9;15:1495540. doi: 10.3389/fimmu.2024.1495540. eCollection 2024. Front Immunol. 2024. PMID: 39717777 Free PMC article. Clinical Trial.
A Phase 1 Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Safety, Tolerability, and Pharmacokinetics of a Respiratory Syncytial Virus Neutralizing Monoclonal Antibody MK-1654 in Healthy Adults.
Aliprantis AO, Wolford D, Caro L, Maas BM, Ma H, Montgomery DL, Sterling LM, Hunt A, Cox KS, Vora KA, Roadcap BA, Railkar RA, Lee AW, Stoch SA, Lai E. Aliprantis AO, et al. Among authors: hunt a. Clin Pharmacol Drug Dev. 2021 May;10(5):556-566. doi: 10.1002/cpdd.883. Epub 2020 Oct 30. Clin Pharmacol Drug Dev. 2021. PMID: 33125189 Clinical Trial.
Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers.
Yin W, Ballard TE, Zhu SX, Hsiao S, Chen H, Li Y, Chowdhury SK, Stevenson A, Hui T, Hunt A, Asgharnejad M, Han S. Yin W, et al. Among authors: hunt a. Br J Clin Pharmacol. 2024 Feb;90(2):516-527. doi: 10.1111/bcp.15917. Epub 2023 Nov 12. Br J Clin Pharmacol. 2024. PMID: 37771051 Clinical Trial.
1,736 results