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An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.
Chapple RH, Liu X, Natarajan S, Alexander MIM, Kim Y, Patel AG, LaFlamme CW, Pan M, Wright WC, Lee HM, Zhang Y, Lu M, Koo SC, Long C, Harper J, Savage C, Johnson MD, Confer T, Akers WJ, Dyer MA, Sheppard H, Easton J, Geeleher P. Chapple RH, et al. Among authors: easton j. bioRxiv [Preprint]. 2024 Apr 22:2023.04.13.536639. doi: 10.1101/2023.04.13.536639. bioRxiv. 2024. Update in: Genome Biol. 2024 Jun 19;25(1):161. doi: 10.1186/s13059-024-03309-4 PMID: 38712039 Free PMC article. Updated. Preprint.
Conditional c-MYC activation in catecholaminergic cells drives distinct neuroendocrine tumors: neuroblastoma vs somatostatinoma.
Wang T, Liu L, Fang J, Jin H, Natarajan S, Sheppard H, Lu M, Turner G, Confer T, Johnson M, Steinberg J, Ha L, Yadak N, Jain R, Picketts DJ, Ma X, Murphy A, Davidoff AM, Glazer ES, Easton J, Chen X, Wang R, Yang J. Wang T, et al. Among authors: easton j. bioRxiv [Preprint]. 2024 Mar 14:2024.03.12.584622. doi: 10.1101/2024.03.12.584622. bioRxiv. 2024. Update in: Cancer Res. 2024 Nov 12. doi: 10.1158/0008-5472.CAN-24-1142 PMID: 38559042 Free PMC article. Updated. Preprint.
Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid.
Pan M, Zhang Y, Wright WC, Liu X, Passaia B, Currier D, Low J, Chapple RH, Steele JA, Connelly JP, Lu M, Lee HM, Loughran AJ, Yang L, Abraham BJ, Pruett-Miller SM, Freeman B, Campbell GE, Dyer MA, Chen T, Stewart E, Koo S, Sheppard H, Easton J, Geeleher P. Pan M, et al. Among authors: easton j. bioRxiv [Preprint]. 2024 May 14:2024.05.09.593394. doi: 10.1101/2024.05.09.593394. bioRxiv. 2024. PMID: 38798584 Free PMC article. Preprint.
SJPedPanel: A pan-cancer gene panel for childhood malignancies.
Kolekar P, Balagopal V, Dong L, Liu Y, Foy S, Tran Q, Mulder H, Huskey AL, Plyler E, Liang Z, Ma J, Nakitandwe J, Gu J, Namwanje M, Maciaszek J, Payne-Turner D, Mallampati S, Wang L, Easton J, Klco JM, Ma X. Kolekar P, et al. Among authors: easton j. medRxiv [Preprint]. 2024 Feb 9:2023.11.27.23299068. doi: 10.1101/2023.11.27.23299068. medRxiv. 2024. Update in: Clin Cancer Res. 2024 Sep 13;30(18):4100-4114. doi: 10.1158/1078-0432.CCR-24-1063 PMID: 38076942 Free PMC article. Updated. Preprint.
Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma.
Wang T, Liu L, Fang J, Jin H, Natarajan S, Sheppard H, Lu M, Turner G, Confer T, Johnson M, Steinberg J, Ha L, Yadak N, Jain R, Picketts DJ, Ma X, Murphy A, Davidoff AM, Glazer ES, Easton J, Chen X, Wang R, Yang J. Wang T, et al. Among authors: easton j. Cancer Res. 2024 Nov 12. doi: 10.1158/0008-5472.CAN-24-1142. Online ahead of print. Cancer Res. 2024. PMID: 39531507
Response to PARP Inhibition in BARD1-Mutated Refractory Neuroblastoma.
Cupit-Link M, Hagiwara K, Nagy M, Koo SC, Orr BA, Ruppin E, Easton J, Zhang J, Federico SM. Cupit-Link M, et al. Among authors: easton j. N Engl J Med. 2024 Aug 15;391(7):659-661. doi: 10.1056/NEJMc2403316. N Engl J Med. 2024. PMID: 39141861 Free PMC article. No abstract available.
SJPedPanel: A Pan-Cancer Gene Panel for Childhood Malignancies to Enhance Cancer Monitoring and Early Detection.
Kolekar P, Balagopal V, Dong L, Liu Y, Foy S, Tran Q, Mulder H, Huskey ALW, Plyler E, Liang Z, Ma J, Nakitandwe J, Gu J, Namwanje M, Maciaszek J, Payne-Turner D, Mallampati S, Wang L, Easton J, Klco JM, Ma X. Kolekar P, et al. Among authors: easton j. Clin Cancer Res. 2024 Sep 13;30(18):4100-4114. doi: 10.1158/1078-0432.CCR-24-1063. Clin Cancer Res. 2024. PMID: 39047169 Free PMC article.
Race and Ethnicity, Socioeconomic Factors, and Epigenetic Age Acceleration in Survivors of Childhood Cancer.
Chen C, Plonski NM, Dong Q, Song N, Zhang X, Parikh HM, Finch ER, Easton J, Mulder HL, Walker E, Neale G, Pan Y, Li Q, Zhang J, Krull K, Robison LL, Armstrong GT, Yasui Y, Ness KK, Hudson MM, Wang H, Huang IC, Wang Z. Chen C, et al. Among authors: easton j. JAMA Netw Open. 2024 Jul 1;7(7):e2419771. doi: 10.1001/jamanetworkopen.2024.19771. JAMA Netw Open. 2024. PMID: 38954412 Free PMC article.
557 results