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Page 1
A spike virosome vaccine induces pan-sarbecovirus antibody responses in mice.
Brinkkemper M, Poniman M, Siteur-van Rijnstra E, Iddouch WA, Bijl TPL, Guerra D, Tejjani K, Grobben M, Bhoelan F, Bemelman D, Kempers R, van Gils MJ, Sliepen K, Stegmann T, van der Velden YU, Sanders RW. Brinkkemper M, et al. Among authors: sliepen k. iScience. 2024 Apr 10;27(5):109719. doi: 10.1016/j.isci.2024.109719. eCollection 2024 May 17. iScience. 2024. PMID: 38706848 Free PMC article.
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB. Blattner C, et al. Among authors: sliepen k. Immunity. 2014 May 15;40(5):669-80. doi: 10.1016/j.immuni.2014.04.008. Epub 2014 Apr 24. Immunity. 2014. PMID: 24768348 Free PMC article.
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M. Huang J, et al. Among authors: sliepen k. Nature. 2014 Nov 6;515(7525):138-42. doi: 10.1038/nature13601. Epub 2014 Sep 3. Nature. 2014. PMID: 25186731 Free PMC article.
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW. Derking R, et al. Among authors: sliepen k. PLoS Pathog. 2015 Mar 25;11(3):e1004767. doi: 10.1371/journal.ppat.1004767. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25807248 Free PMC article.
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Kong L, Torrents de la Peña A, Deller MC, Garces F, Sliepen K, Hua Y, Stanfield RL, Sanders RW, Wilson IA. Kong L, et al. Among authors: sliepen k. Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2099-108. doi: 10.1107/S1399004715013917. Epub 2015 Sep 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26457433 Free PMC article.
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