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Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1α/Lipin1 axis in an aging-related sarcopenia model.
Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Chung HJ, Blair NS, Millay DP, Morris AJ, Prideaux B, Finck BN, Quattrocelli M. Prabakaran AD, et al. Among authors: finck bn. J Clin Invest. 2024 May 3;134(11):e177427. doi: 10.1172/JCI177427. J Clin Invest. 2024. PMID: 38702076 Free PMC article.
Glucocorticoid intermittence coordinates rescue of energy and mass in aging-related sarcopenia through the myocyte-autonomous PGC1alpha-Lipin1 transactivation.
Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Blair NS, Millay DP, Prideaux B, Finck BN, Quattrocelli M. Prabakaran AD, et al. Among authors: finck bn. bioRxiv [Preprint]. 2023 Oct 19:2023.10.16.562573. doi: 10.1101/2023.10.16.562573. bioRxiv. 2023. PMID: 37905062 Free PMC article. Preprint.
In chronic kidney disease altered cardiac metabolism precedes cardiac hypertrophy.
Williams MJ, Halabi CM, Patel HM, Joseph Z, McCommis K, Weinheimer C, Kovacs A, Lima F, Finck B, Malluche H, Hruska KA. Williams MJ, et al. Am J Physiol Renal Physiol. 2024 May 1;326(5):F751-F767. doi: 10.1152/ajprenal.00416.2023. Epub 2024 Feb 22. Am J Physiol Renal Physiol. 2024. PMID: 38385175
Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult.
Yiew NKH, Vazquez JH, Martino MR, Kennon-McGill S, Price JR, Allard FD, Yee EU, Layman AJ, James LP, McCommis KS, Finck BN, McGill MR. Yiew NKH, et al. Among authors: finck bn. Mol Metab. 2023 Nov;77:101808. doi: 10.1016/j.molmet.2023.101808. Epub 2023 Sep 15. Mol Metab. 2023. PMID: 37716594 Free PMC article.
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier.
Maram L, Michael JM, Politte H, Srirama VS, Hadji A, Habibi M, Kelly MO, Brookheart RT, Finck BN, Hegazy L, McCommis KS, Elgendy B. Maram L, et al. Among authors: finck bn. Eur J Med Chem. 2025 Feb 5;283:117150. doi: 10.1016/j.ejmech.2024.117150. Epub 2024 Dec 11. Eur J Med Chem. 2025. PMID: 39708766 Free article.
176 results