Molkentin JD - Search Results

1

MCU genetically altered mice suggest how mitochondrial Ca²⁺ regulates metabolism.

Huo J, Molkentin JD. Huo J, et al. Among authors: molkentin jd. Trends Endocrinol Metab. 2024 Oct;35(10):918-928. doi: 10.1016/j.tem.2024.04.005. Epub 2024 Apr 29. Trends Endocrinol Metab. 2024. PMID: 38688781 Review.

2

Rpl3l gene deletion in mice reduces heart weight over time.

Grimes KM, Prasad V, Huo J, Kuwabara Y, Vanhoutte D, Baldwin TA, Bowers SLK, Johansen AKZ, Sargent MA, Lin SJ, Molkentin JD. Grimes KM, et al. Among authors: molkentin jd. Front Physiol. 2023 Jan 17;14:1054169. doi: 10.3389/fphys.2023.1054169. eCollection 2023. Front Physiol. 2023. PMID: 36733907 Free PMC article.

3

MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle.

Huo J, Prasad V, Grimes KM, Vanhoutte D, Blair NS, Lin SC, Bround MJ, Bers DM, Molkentin JD. Huo J, et al. Among authors: molkentin jd. Cell Rep. 2023 Nov 28;42(11):113465. doi: 10.1016/j.celrep.2023.113465. Epub 2023 Nov 16. Cell Rep. 2023. PMID: 37976157 Free PMC article.

4

MCU-independent Ca²⁺ uptake mediates mitochondrial Ca²⁺ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy.

Bround MJ, Abay E, Huo J, Havens JR, York AJ, Bers DM, Molkentin JD. Bround MJ, et al. Among authors: molkentin jd. Sci Rep. 2024 Mar 21;14(1):6751. doi: 10.1038/s41598-024-57340-3. Sci Rep. 2024. PMID: 38514795 Free PMC article.

5

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner.

Vanhoutte D, Schips TG, Minerath RA, Huo J, Kavuri NSS, Prasad V, Lin SC, Bround MJ, Sargent MA, Adams CM, Molkentin JD. Vanhoutte D, et al. Among authors: molkentin jd. Cell Rep. 2024 May 28;43(5):114149. doi: 10.1016/j.celrep.2024.114149. Epub 2024 Apr 26. Cell Rep. 2024. PMID: 38678560 Free PMC article.

6

MICU1 and MICU2, two peas in a pod or entirely different fruits?

Huo J, Molkentin JD. Huo J, et al. Among authors: molkentin jd. Cell Calcium. 2024 Dec;124:102959. doi: 10.1016/j.ceca.2024.102959. Epub 2024 Oct 8. Cell Calcium. 2024. PMID: 39405656

7

EMC3 regulates trafficking and pulmonary toxicity of the SFTPCI73T mutation associated with interstitial lung disease.

Tang X, Wei W, Sun Y, Weaver TE, Nakayasu ES, Clair G, Snowball JM, Na CL, Apsley KS, Martin EP, Kotton DN, Alysandratos KD, Huo J, Molkentin JD, Gower WA, Lin X, Whitsett JA. Tang X, et al. Among authors: molkentin jd. J Clin Invest. 2024 Oct 15;134(23):e173861. doi: 10.1172/JCI173861. J Clin Invest. 2024. PMID: 39405113 Free PMC article.

8

MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network.

Grimes KM, Maillet M, Swoboda CO, Bowers SLK, Millay DP, Molkentin JD. Grimes KM, et al. Among authors: molkentin jd. Am J Physiol Heart Circ Physiol. 2024 Jan 1;326(1):H180-H189. doi: 10.1152/ajpheart.00612.2023. Epub 2023 Nov 24. Am J Physiol Heart Circ Physiol. 2024. PMID: 37999644 Free PMC article.

9

A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.

Kuwabara Y, York AJ, Lin SC, Sargent MA, Grimes KM, Pirruccello JP, Molkentin JD. Kuwabara Y, et al. Among authors: molkentin jd. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2213696120. doi: 10.1073/pnas.2213696120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126682 Free PMC article.

10

Palmitoylation-dependent regulation of cardiomyocyte Rac1 signaling activity and minor effects on cardiac hypertrophy.

Baldwin TA, Teuber JP, Kuwabara Y, Subramani A, Lin SJ, Kanisicak O, Vagnozzi RJ, Zhang W, Brody MJ, Molkentin JD. Baldwin TA, et al. Among authors: molkentin jd. J Biol Chem. 2023 Dec;299(12):105426. doi: 10.1016/j.jbc.2023.105426. Epub 2023 Nov 3. J Biol Chem. 2023. PMID: 37926281 Free PMC article.

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