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Differential Effects of HDAC6 Inhibition Versus Knockout During Hepatic Ischemia-Reperfusion Injury Highlight Importance of HDAC6 C-terminal Zinc-finger Ubiquitin-binding Domain.
Concors SJ, Hernandez PT, O'Brien C, DePaolo J, Murken DR, Aufhauser DD, Wang Z, Xiong Y, Krumeich L, Ge G, Beier UH, Bhatti TR, Kozikowski AP, Avelar LAA, Kurz T, Hancock WW, Levine MH. Concors SJ, et al. Among authors: wang z. Transplantation. 2024 Oct 1;108(10):2084-2092. doi: 10.1097/TP.0000000000005042. Epub 2024 Sep 24. Transplantation. 2024. PMID: 38685198
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
Aufhauser DD Jr, Hernandez P, Concors SJ, O'Brien C, Wang Z, Murken DR, Samanta A, Beier UH, Krumeich L, Bhatti TR, Wang Y, Ge G, Wang L, Cheraghlou S, Wagner FF, Holson EB, Kalin JH, Cole PA, Hancock WW, Levine MH. Aufhauser DD Jr, et al. Among authors: wang l, wang z, wang y. Sci Rep. 2021 Apr 27;11(1):9018. doi: 10.1038/s41598-021-88242-3. Sci Rep. 2021. PMID: 33907245 Free PMC article.
Targeting Sirtuin-1 prolongs murine renal allograft survival and function.
Levine MH, Wang Z, Xiao H, Jiao J, Wang L, Bhatti TR, Hancock WW, Beier UH. Levine MH, et al. Among authors: wang l, wang z. Kidney Int. 2016 May;89(5):1016-1026. doi: 10.1016/j.kint.2015.12.051. Epub 2016 Mar 16. Kidney Int. 2016. PMID: 27083279 Free PMC article.
Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.
Akimova T, Zhang T, Christensen LM, Wang Z, Han R, Negorev D, Samanta A, Sasson IE, Gaddapara T, Jiao J, Wang L, Bhatti TR, Levine MH, Diamond JM, Beier UH, Simmons RA, Cantu E, Wilkes DS, Lederer DJ, Anderson M, Christie JD, Hancock WW. Akimova T, et al. Among authors: wang l, wang z. Am J Respir Crit Care Med. 2021 Nov 1;204(9):1060-1074. doi: 10.1164/rccm.202012-4306OC. Am J Respir Crit Care Med. 2021. PMID: 34346860 Free PMC article.
Improved renal ischemia tolerance in females influences kidney transplantation outcomes.
Aufhauser DD Jr, Wang Z, Murken DR, Bhatti TR, Wang Y, Ge G, Redfield RR 3rd, Abt PL, Wang L, Svoronos N, Thomasson A, Reese PP, Hancock WW, Levine MH. Aufhauser DD Jr, et al. Among authors: wang l, wang z, wang y. J Clin Invest. 2016 May 2;126(5):1968-77. doi: 10.1172/JCI84712. Epub 2016 Apr 18. J Clin Invest. 2016. PMID: 27088798 Free PMC article.
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.
Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH. Angelin A, et al. Among authors: wang l, wang z. Cell Metab. 2017 Jun 6;25(6):1282-1293.e7. doi: 10.1016/j.cmet.2016.12.018. Epub 2017 Apr 13. Cell Metab. 2017. PMID: 28416194 Free PMC article.
Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
Quinn WJ 3rd, Jiao J, TeSlaa T, Stadanlick J, Wang Z, Wang L, Akimova T, Angelin A, Schäfer PM, Cully MD, Perry C, Kopinski PK, Guo L, Blair IA, Ghanem LR, Leibowitz MS, Hancock WW, Moon EK, Levine MH, Eruslanov EB, Wallace DC, Baur JA, Beier UH. Quinn WJ 3rd, et al. Among authors: wang l, wang z. Cell Rep. 2020 Dec 15;33(11):108500. doi: 10.1016/j.celrep.2020.108500. Cell Rep. 2020. PMID: 33326785 Free PMC article.
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