Trippier PC - Search Results

1

Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader.

Carmona AV, Jonnalagadda S, Case AM, Maddeboina K, Jonnalagadda SK, Dow LF, Duan L, Penning TM, Trippier PC. Carmona AV, et al. Among authors: trippier pc. Commun Chem. 2024 Apr 29;7(1):95. doi: 10.1038/s42004-024-01177-4. Commun Chem. 2024. PMID: 38684887 Free PMC article.

2

Screening baccharin analogs as selective inhibitors against type 5 17β-hydroxysteroid dehydrogenase (AKR1C3).

Zang T, Verma K, Chen M, Jin Y, Trippier PC, Penning TM. Zang T, et al. Among authors: trippier pc. Chem Biol Interact. 2015 Jun 5;234:339-48. doi: 10.1016/j.cbi.2014.12.015. Epub 2014 Dec 31. Chem Biol Interact. 2015. PMID: 25555457 Free PMC article.

3

Selective AKR1C3 Inhibitors Potentiate Chemotherapeutic Activity in Multiple Acute Myeloid Leukemia (AML) Cell Lines.

Verma K, Zang T, Gupta N, Penning TM, Trippier PC. Verma K, et al. Among authors: trippier pc. ACS Med Chem Lett. 2016 Jun 22;7(8):774-9. doi: 10.1021/acsmedchemlett.6b00163. eCollection 2016 Aug 11. ACS Med Chem Lett. 2016. PMID: 27563402 Free PMC article.

4

AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells.

Verma K, Gupta N, Zang T, Wangtrakluldee P, Srivastava SK, Penning TM, Trippier PC. Verma K, et al. Among authors: trippier pc. Mol Cancer Ther. 2018 Sep;17(9):1833-1845. doi: 10.1158/1535-7163.MCT-17-1023. Epub 2018 Jun 11. Mol Cancer Ther. 2018. PMID: 29891491

5

Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia.

Verma K, Zang T, Penning TM, Trippier PC. Verma K, et al. Among authors: trippier pc. J Med Chem. 2019 Apr 11;62(7):3590-3616. doi: 10.1021/acs.jmedchem.9b00090. Epub 2019 Mar 25. J Med Chem. 2019. PMID: 30836001 Free PMC article.

6

Reversal of Apalutamide and Darolutamide Aldo-Keto Reductase 1C3-Mediated Resistance by a Small Molecule Inhibitor.

Morsy A, Trippier PC. Morsy A, et al. Among authors: trippier pc. ACS Chem Biol. 2020 Mar 20;15(3):646-650. doi: 10.1021/acschembio.0c00069. Epub 2020 Mar 9. ACS Chem Biol. 2020. PMID: 32125151 Free PMC article.

7

Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.

Kumari S, Carmona AV, Tiwari AK, Trippier PC. Kumari S, et al. Among authors: trippier pc. J Med Chem. 2020 Nov 12;63(21):12290-12358. doi: 10.1021/acs.jmedchem.0c00530. Epub 2020 Aug 4. J Med Chem. 2020. PMID: 32686940 Free PMC article. Review.

8

Exogenous Flupirtine as Potential Treatment for CLN3 Disease.

Maalouf K, Makoukji J, Saab S, Makhoul NJ, Carmona AV, Kinarivala N, Ghanem N, Trippier PC, Boustany RM. Maalouf K, et al. Among authors: trippier pc. Cells. 2020 Aug 11;9(8):1872. doi: 10.3390/cells9081872. Cells. 2020. PMID: 32796515 Free PMC article.

9

An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening.

Kinarivala N, Morsy A, Patel R, Carmona AV, Sajib MS, Raut S, Mikelis CM, Al-Ahmad A, Trippier PC. Kinarivala N, et al. Among authors: trippier pc. ACS Pharmacol Transl Sci. 2020 Sep 1;3(5):931-947. doi: 10.1021/acsptsci.0c00077. eCollection 2020 Oct 9. ACS Pharmacol Transl Sci. 2020. PMID: 33073192 Free PMC article.

10

Aldo-Keto Reductases and Cancer Drug Resistance.

Penning TM, Jonnalagadda S, Trippier PC, Rižner TL. Penning TM, et al. Among authors: trippier pc. Pharmacol Rev. 2021 Jul;73(3):1150-1171. doi: 10.1124/pharmrev.120.000122. Pharmacol Rev. 2021. PMID: 34312303 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

59 results

Search Page

Filters