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Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia.
Spathopoulou A, Sauerwein GA, Marteau V, Podlesnic M, Lindlbauer T, Kipura T, Hotze M, Gabassi E, Kruszewski K, Koskuvi M, Réthelyi JM, Apáti Á, Conti L, Ku M, Koal T, Müller U, Talmazan RA, Ojansuu I, Vaurio O, Lähteenvuo M, Lehtonen Š, Mertens J, Kwiatkowski M, Günther K, Tiihonen J, Koistinaho J, Trajanoski Z, Edenhofer F. Spathopoulou A, et al. Among authors: koistinaho j. Mol Psychiatry. 2024 Oct;29(10):3128-3140. doi: 10.1038/s41380-024-02568-8. Epub 2024 Apr 29. Mol Psychiatry. 2024. PMID: 38684795 Free PMC article.
Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice With Contusion Spinal Cord Injury.
Pomeshchik Y, Puttonen KA, Kidin I, Ruponen M, Lehtonen S, Malm T, Åkesson E, Hovatta O, Koistinaho J. Pomeshchik Y, et al. Among authors: koistinaho j. Cell Transplant. 2015;24(9):1799-812. doi: 10.3727/096368914X684079. Epub 2014 Sep 8. Cell Transplant. 2015. PMID: 25203632 Free article.
PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.
Oksanen M, Petersen AJ, Naumenko N, Puttonen K, Lehtonen Š, Gubert Olivé M, Shakirzyanova A, Leskelä S, Sarajärvi T, Viitanen M, Rinne JO, Hiltunen M, Haapasalo A, Giniatullin R, Tavi P, Zhang SC, Kanninen KM, Hämäläinen RH, Koistinaho J. Oksanen M, et al. Among authors: koistinaho j. Stem Cell Reports. 2017 Dec 12;9(6):1885-1897. doi: 10.1016/j.stemcr.2017.10.016. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153989 Free PMC article.
Generation of a human induced pluripotent stem cell line from a patient with a rare A673T variant in amyloid precursor protein gene that reduces the risk for Alzheimer's disease.
Lehtonen Š, Höytyläinen I, Voutilainen J, Sonninen TM, Kuusisto J, Laakso M, Hämäläinen RH, Oksanen M, Koistinaho J. Lehtonen Š, et al. Among authors: koistinaho j. Stem Cell Res. 2018 Jul;30:96-99. doi: 10.1016/j.scr.2018.05.014. Epub 2018 May 19. Stem Cell Res. 2018. PMID: 29807259 Free article.
Generation of a human induced pluripotent stem cell line (LL008 1.4) from a familial Alzheimer's disease patient carrying a double KM670/671NL (Swedish) mutation in APP gene.
Oksanen M, Hyötyläinen I, Voutilainen J, Puttonen KA, Hämäläinen RH, Graff C, Lehtonen Š, Koistinaho J. Oksanen M, et al. Among authors: koistinaho j. Stem Cell Res. 2018 Aug;31:181-185. doi: 10.1016/j.scr.2018.07.024. Epub 2018 Aug 1. Stem Cell Res. 2018. PMID: 30099334 Free article.
Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis.
Korhonen P, Pollari E, Kanninen KM, Savchenko E, Lehtonen Š, Wojciechowski S, Pomeshchik Y, Van Den Bosch L, Goldsteins G, Koistinaho J, Malm T. Korhonen P, et al. Among authors: koistinaho j. IBRO Rep. 2019 Jan 11;6:74-86. doi: 10.1016/j.ibror.2019.01.005. eCollection 2019 Jun. IBRO Rep. 2019. PMID: 30705990 Free PMC article.
293 results