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Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy.
Rodríguez-Hernández MÁ, Baena-Bustos M, Carneros D, Zurita-Palomo C, Muñoz-Pinillos P, Millán J, Padillo FJ, Smerdou C, von Kobbe C, Rose-John S, Bustos M. Rodríguez-Hernández MÁ, et al. Among authors: munoz pinillos p. EBioMedicine. 2024 May;103:105132. doi: 10.1016/j.ebiom.2024.105132. Epub 2024 Apr 26. EBioMedicine. 2024. PMID: 38677182 Free PMC article.
Simultaneous Targeting of IL-1-Signaling and IL-6-Trans-Signaling Preserves Human Pulmonary Endothelial Barrier Function During a Cytokine Storm-Brief Report.
Colás-Algora N, Muñoz-Pinillos P, Cacho-Navas C, Avendaño-Ortiz J, de Rivas G, Barroso S, López-Collazo E, Millán J. Colás-Algora N, et al. Among authors: munoz pinillos p. Arterioscler Thromb Vasc Biol. 2023 Nov;43(11):2213-2222. doi: 10.1161/ATVBAHA.123.319695. Epub 2023 Sep 21. Arterioscler Thromb Vasc Biol. 2023. PMID: 37732482 Free article.