Parkins A - Search Results

1

The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.

Parkins A, Pilien AVR, Wolff AM, Argueta C, Vargas J, Sadeghi S, Franz AH, Thompson MC, Pantouris G. Parkins A, et al. J Med Chem. 2024 May 9;67(9):7359-7372. doi: 10.1021/acs.jmedchem.4c00177. Epub 2024 Apr 26. J Med Chem. 2024. PMID: 38670943

2

The N-terminus of MIF regulates the dynamic profile of residues involved in CD74 activation.

Parkins A, Skeens E, McCallum CM, Lisi GP, Pantouris G. Parkins A, et al. Biophys J. 2021 Sep 21;120(18):3893-3900. doi: 10.1016/j.bpj.2021.08.025. Epub 2021 Aug 24. Biophys J. 2021. PMID: 34437846 Free PMC article.

3

Ligand-induced conformational changes enable intersubunit communications in D-dopachrome tautomerase.

Parkins A, Chen E, Rangel VM, Singh M, Xue L, Lisi GP, Pantouris G. Parkins A, et al. Biophys J. 2023 Apr 4;122(7):1268-1276. doi: 10.1016/j.bpj.2023.02.019. Epub 2023 Feb 17. Biophys J. 2023. PMID: 36804669 Free PMC article.

4

2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase.

Parkins A, Das P, Prahaladan V, Rangel VM, Xue L, Sankaran B, Bhandari V, Pantouris G. Parkins A, et al. Structure. 2023 Mar 2;31(3):355-367.e4. doi: 10.1016/j.str.2023.01.008. Epub 2023 Feb 17. Structure. 2023. PMID: 36805127 Free article.

5

Underrepresented Impurities in 4-Hydroxyphenylpyruvate Affect the Catalytic Activity of Multiple Enzymes.

Parkins A, Sandin SI, Knittel J, Franz AH, Ren J, de Alba E, Pantouris G. Parkins A, et al. Anal Chem. 2023 Mar 21;95(11):4957-4965. doi: 10.1021/acs.analchem.2c04969. Epub 2023 Mar 6. Anal Chem. 2023. PMID: 36877482

6

A novel enzymatic assay for the identification of 4-hydroxyphenylpyruvate dioxygenase modulators.

Parkins A, Pantouris G. Parkins A, et al. STAR Protoc. 2023 May 10;4(2):102300. doi: 10.1016/j.xpro.2023.102300. Online ahead of print. STAR Protoc. 2023. PMID: 37167058 Free PMC article.

7

Protocol for purification and enzymatic characterization of members of the human macrophage migration inhibitory factor superfamily.

Parkins A, Pantouris G. Parkins A, et al. STAR Protoc. 2023 Sep 15;4(3):102375. doi: 10.1016/j.xpro.2023.102375. Epub 2023 Jun 24. STAR Protoc. 2023. PMID: 37355993 Free PMC article.

8

Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose.

Bloom J, Pantouris G, He M, Aljabari B, Mishra L, Manjula R, Parkins A, Lolis EJ, Al-Abed Y. Bloom J, et al. Among authors: parkins a. Mol Med. 2024 Mar 27;30(1):43. doi: 10.1186/s10020-024-00803-0. Mol Med. 2024. PMID: 38539088 Free PMC article.

9

Conformational Flexibility of the C-Terminal Region Influences Distal Active Site Residues Across the Tautomerase Superfamily.

Argueta C, Parkins A, Pantouris G. Argueta C, et al. Among authors: parkins a. Int J Mol Sci. 2024 Nov 24;25(23):12617. doi: 10.3390/ijms252312617. Int J Mol Sci. 2024. PMID: 39684328 Free PMC article.

10

Observation of Magic Number Clusters from Thermal Dissociation Molecular Dynamics Simulations of Lithium Formate Ionic Clusters.

Zhang J, Bogdanov B, Parkins A, McCallum CM. Zhang J, et al. Among authors: parkins a. J Phys Chem A. 2020 May 7;124(18):3535-3541. doi: 10.1021/acs.jpca.0c01973. Epub 2020 Apr 23. J Phys Chem A. 2020. PMID: 32286071

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