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Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy.
Wang-Bishop L, Wehbe M, Pastora LE, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Roth EW, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT. Wang-Bishop L, et al. Among authors: fedorova o. ACS Nano. 2024 May 7;18(18):11631-11643. doi: 10.1021/acsnano.3c06225. Epub 2024 Apr 23. ACS Nano. 2024. PMID: 38652829 Free PMC article.
A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice.
Mao T, Israelow B, Lucas C, Vogels CBF, Fedorova O, Breban MI, Menasche BL, Dong H, Linehan M; Yale SARS-CoV-2 Genome Surveillance Initiative; Wilen CB, Landry ML, Grubaugh ND, Pyle AM, Iwasaki A. Mao T, et al. Among authors: fedorova o. bioRxiv [Preprint]. 2021 Jun 17:2021.06.16.448754. doi: 10.1101/2021.06.16.448754. bioRxiv. 2021. Update in: J Exp Med. 2022 Jan 3;219(1):e20211818. doi: 10.1084/jem.20211818. PMID: 34159330 Free PMC article. Updated. Preprint.
Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.
Palmer CR, Pastora LE, Kimmel BR, Pagendarm HM, Kwiatkowski AJ, Stone PT, Arora K, Francini N, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: fedorova o. Adv Healthc Mater. 2024 Apr 22:e2303815. doi: 10.1002/adhm.202303815. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38648653
Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers.
Huseman ED, Lo A, Fedorova O, Elia JL, Gueble SE, Lin K, Sundaram RK, Oh J, Liu J, Menges F, Rees MG, Ronan MM, Roth JA, Batista VS, Crawford JM, Pyle AM, Bindra RS, Herzon SB. Huseman ED, et al. Among authors: fedorova o. J Am Chem Soc. 2024 Jul 10;146(27):18241-18252. doi: 10.1021/jacs.3c06483. Epub 2024 May 30. J Am Chem Soc. 2024. PMID: 38815248
Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN Domain.
Small GI, Fedorova O, Olinares PDB, Chandanani J, Banerjee A, Choi YJ, Molina H, Chait B, Darst SA, Campbell EA. Small GI, et al. Among authors: fedorova o. bioRxiv [Preprint]. 2023 Sep 26:2023.09.25.558837. doi: 10.1101/2023.09.25.558837. bioRxiv. 2023. Update in: Mol Cell. 2023 Nov 2;83(21):3921-3930.e7. doi: 10.1016/j.molcel.2023.10.001. PMID: 37808858 Free PMC article. Updated. Preprint.
MDM2 up-regulates the energy metabolism in NSCLC in a p53-independent manner.
Fefilova E, Kirdeeva Y, Parfenyev S, Daks A, Fedorova O, Sorokina M, Ha NX, Huong TT, Loc VT, Hai PT, Cuong NM, Barlev N, Shuvalov O. Fefilova E, et al. Among authors: fedorova o. Biochem Biophys Res Commun. 2025 Jan;743:151169. doi: 10.1016/j.bbrc.2024.151169. Epub 2024 Dec 12. Biochem Biophys Res Commun. 2025. PMID: 39693937
593 results