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A de novo dominant-negative variant is associated with OTULIN-related autoinflammatory syndrome.
Takeda Y, Ueki M, Matsuhiro J, Walinda E, Tanaka T, Yamada M, Fujita H, Takezaki S, Kobayashi I, Tamaki S, Nagata S, Miyake N, Matsumoto N, Osawa M, Yasumi T, Heike T, Ohtake F, Saito MK, Toguchida J, Takita J, Ariga T, Iwai K. Takeda Y, et al. Among authors: ohtake f. J Exp Med. 2024 Jun 3;221(6):e20231941. doi: 10.1084/jem.20231941. Epub 2024 Apr 23. J Exp Med. 2024. PMID: 38652464 Free PMC article.
cIAP1-based degraders induce degradation via branched ubiquitin architectures.
Akizuki Y, Morita M, Mori Y, Kaiho-Soma A, Dixit S, Endo A, Shimogawa M, Hayashi G, Naito M, Okamoto A, Tanaka K, Saeki Y, Ohtake F. Akizuki Y, et al. Among authors: ohtake f. Nat Chem Biol. 2023 Mar;19(3):311-322. doi: 10.1038/s41589-022-01178-1. Epub 2022 Oct 31. Nat Chem Biol. 2023. PMID: 36316570
GlcNAcylation of histone H2B facilitates its monoubiquitination.
Fujiki R, Hashiba W, Sekine H, Yokoyama A, Chikanishi T, Ito S, Imai Y, Kim J, He HH, Igarashi K, Kanno J, Ohtake F, Kitagawa H, Roeder RG, Brown M, Kato S. Fujiki R, et al. Among authors: ohtake f. Nature. 2011 Nov 27;480(7378):557-60. doi: 10.1038/nature10656. Nature. 2011. PMID: 22121020 Free PMC article.
Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.
Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F. Oikawa D, et al. Among authors: ohtake f. Commun Biol. 2020 Apr 3;3(1):163. doi: 10.1038/s42003-020-0882-8. Commun Biol. 2020. PMID: 32246052 Free PMC article.
80 results