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507 results

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Page 1
A novel DNase assay reveals low DNase activity in severe asthma.
Charbit AR, Liegeois MA, Raymond WW, Comhair SAA, Johansson MW, Hastie AT, Bleecker ER, Fajt M, Castro M, Sumino K, Erzurum SC, Israel E, Jarjour NN, Mauger DT, Moore WC, Wenzel SE, Woodruff PG, Levy BD, Tang MC, Fahy JV. Charbit AR, et al. Among authors: bleecker er. Am J Physiol Lung Cell Mol Physiol. 2024 Jun 1;326(6):L796-L804. doi: 10.1152/ajplung.00081.2024. Epub 2024 Apr 23. Am J Physiol Lung Cell Mol Physiol. 2024. PMID: 38651338
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort.
Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, Barr RG, Carretta EE, Couper DJ, Cooper CB, Hoffman EA, Kanner RE, Kleerup E, O'Neal WK, Paine R 3rd, Peters SP, Alexis NE, Woodruff PG, Han MK, Meyers DA, Bleecker ER; SPIROMICS investigators. Hastie AT, et al. Among authors: bleecker er. Lancet Respir Med. 2017 Dec;5(12):956-967. doi: 10.1016/S2213-2600(17)30432-0. Epub 2017 Nov 13. Lancet Respir Med. 2017. PMID: 29146301 Free PMC article.
Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma.
Tang M, Charbit AR, Johansson MW, Jarjour NN, Denlinger LC, Raymond WW, Peters MC, Dunican EM, Castro M, Sumino K, Erzurum SC, Comhair SA, Moore WC, Levy BD, Israel E, Phipatanakul W, Phillips BR, Mauger DT, Bleecker ER, Wenzel SE, Fajt ML, Woodruff PG, Hastie AT, Fahy JV; National Heart Lung and Blood Institute Severe Asthma Research Program. Tang M, et al. Among authors: bleecker er. J Allergy Clin Immunol. 2024 Sep;154(3):580-591.e6. doi: 10.1016/j.jaci.2024.03.023. Epub 2024 Apr 23. J Allergy Clin Immunol. 2024. PMID: 38663815 Free article.
Anemia and Adverse Outcomes in a Chronic Obstructive Pulmonary Disease Population with a High Burden of Comorbidities. An Analysis from SPIROMICS.
Putcha N, Fawzy A, Paul GG, Lambert AA, Psoter KJ, Sidhaye VK, Woo J, Wells JM, Labaki WW, Doerschuk CM, Kanner RE, Han MK, Martinez C, Paulin LM, Martinez FJ, Wise RA, O'Neal WK, Barr RG, Hansel NN; SPIROMICS investigators. Putcha N, et al. Ann Am Thorac Soc. 2018 Jun;15(6):710-717. doi: 10.1513/AnnalsATS.201708-687OC. Ann Am Thorac Soc. 2018. PMID: 30726108 Free PMC article.
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M; Understanding Society Scientific Group; Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Artigas MS, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers… See abstract for full author list ➔ Shrine N, et al. Among authors: bleecker er. Nat Genet. 2024 May;56(5):1032-1033. doi: 10.1038/s41588-024-01752-4. Nat Genet. 2024. PMID: 38641645 No abstract available.
Oral Glucocorticoid-Sparing Effect of Benralizumab in Severe Asthma.
Nair P, Wenzel S, Rabe KF, Bourdin A, Lugogo NL, Kuna P, Barker P, Sproule S, Ponnarambil S, Goldman M; ZONDA Trial Investigators. Nair P, et al. N Engl J Med. 2017 Jun 22;376(25):2448-2458. doi: 10.1056/NEJMoa1703501. Epub 2017 May 22. N Engl J Med. 2017. PMID: 28530840 Free article. Clinical Trial.
Dynamic and prognostic proteomic associations with FEV1 decline in chronic obstructive pulmonary disease.
Ruvuna L, Hijazi K, Guzman DE, Guo C, Loureiro J, Khokhlovich E, Morris M, Obeidat M, Pratte KA, DiLillo KM, Sharma S, Kechris K, Anzueto A, Barjaktarevic I, Bleecker ER, Casaburi R, Comellas A, Cooper CB, DeMeo DL, Foreman M, Flenaugh EL, Han MK, Hanania NA, Hersh CP, Krishnan JA, Labaki WW, Martinez FJ, O'Neal WK, Paine R 3rd, Peters SP, Woodruff PG, Wells JM, Wendt CH, Arnold KB, Barr RG, Curtis JL, Ngo D, Bowler RP; SPIROMICS, COPDGene and MESA-Lung Investigators. Ruvuna L, et al. Among authors: bleecker er. medRxiv [Preprint]. 2024 Aug 8:2024.08.07.24311507. doi: 10.1101/2024.08.07.24311507. medRxiv. 2024. PMID: 39148837 Free PMC article. Preprint.
Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.
Lee I, Ganesan A, Kalesinskas L, Zheng H, Ahn HC, Christenson S, Erzurum SC, Zein J, Bleecker ER, Meyers DA, Castro M, Fahy JV, Israel E, Jarjour NN, Moore W, Wenzel SE, Mauger DT, Levy BD, Woodruff PG, Ortega VE, Khatri P. Lee I, et al. Among authors: bleecker er. Am J Respir Cell Mol Biol. 2024 Dec 19. doi: 10.1165/rcmb.2024-0125OC. Online ahead of print. Am J Respir Cell Mol Biol. 2024. PMID: 39700523
Type 1 Immune Responses Related to Viral Infection Influence Corticosteroid Response in Asthma.
Fahy JV, Jackson ND, Sajuthi SP, Pruesse E, Moore CM, Everman JL, Rios C, Tang M, Gauthier M, Wenzel SE, Bleecker ER, Castro M, Comhair SA, Erzurum SC, Hastie AT, Moore W, Israel E, Levy BD, Denlinger L, Jarjour NN, Johansson MW, Mauger DT, Phillips BR, Sumino K, Woodruff PG, Peters MC, Seibold MA; National Heart, Lung, and Blood Institute Severe Asthma Research Program-3. Fahy JV, et al. Among authors: bleecker er. Am J Respir Crit Care Med. 2024 Nov 27. doi: 10.1164/rccm.202402-0403OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 39601762
507 results