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Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon.
Martinez-Vega R, Mbacham WF, Ali I, Nji A, Mousa A, Beshir KB, Chopo-Pizarro A, Kaur H, Okell L, Hansson H, Hocke EF, Alifrangis M, Gosling R, Roper C, Sutherland C, Chico RM. Martinez-Vega R, et al. Among authors: hocke ef. BMC Infect Dis. 2024 Sep 26;24(1):1028. doi: 10.1186/s12879-024-09868-y. BMC Infect Dis. 2024. PMID: 39327613 Free PMC article. Clinical Trial.
Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology.
Mousa A, Cuomo-Dannenburg G, Thompson HA, Chico RM, Beshir KB, Sutherland CJ, Schellenberg D, Gosling R, Alifrangis M, Hocke EF, Hansson H, Chopo-Pizarro A, Mbacham WF, Ali IM, Chaponda M, Roper C, Okell LC. Mousa A, et al. Among authors: hocke ef. PLoS Med. 2024 May 9;21(5):e1004376. doi: 10.1371/journal.pmed.1004376. eCollection 2024 May. PLoS Med. 2024. PMID: 38723040 Free PMC article.
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Duchatel RJ, Jackson ER, Parackal SG, Kiltschewskij D, Findlay IJ, Mannan A, Staudt DE, Thomas BC, Germon ZP, Laternser S, Kearney PS, Jamaluddin MFB, Douglas AM, Beitaki T, McEwen HP, Persson ML, Hocke EA, Jain V, Aksu M, Manning EE, Murray HC, Verrills NM, Sun CX, Daniel P, Vilain RE, Skerrett-Byrne DA, Nixon B, Hua S, de Bock CE, Colino-Sanguino Y, Valdes-Mora F, Tsoli M, Ziegler DS, Cairns MJ, Raabe EH, Vitanza NA, Hulleman E, Phoenix TN, Koschmann C, Alvaro F, Dayas CV, Tinkle CL, Wheeler H, Whittle JR, Eisenstat DD, Firestein R, Mueller S, Valvi S, Hansford JR, Ashley DM, Gregory SG, Kilburn LB, Nazarian J, Cain JE, Dun MD. Duchatel RJ, et al. Among authors: hocke ea. J Clin Invest. 2024 Feb 6;134(6):e170329. doi: 10.1172/JCI170329. J Clin Invest. 2024. PMID: 38319732 Free PMC article.
Ataxia-telangiectasia mutated ( Atm ) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy.
Mangoli A, Wu S, Liu HQ, Aksu M, Jain V, Foreman BE, Regal JA, Weidenhammer LB, Stewart CE, Guerra Garcia ME, Hocke E, Abramson K, Williams NT, Luo L, Deland K, Attardi L, Abe K, Hashizume R, Ashley DM, Becher OJ, Kirsch DG, Gregory SG, Reitman ZJ. Mangoli A, et al. Among authors: hocke e. bioRxiv [Preprint]. 2023 Oct 20:2023.10.18.562892. doi: 10.1101/2023.10.18.562892. bioRxiv. 2023. PMID: 37904990 Free PMC article. Preprint.
Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon.
Niba PTN, Nji AM, Chedjou JPK, Hansson H, Hocke EF, Ali IM, Achonduh-Atijegbe O, Evehe MB, Jørgensen MHM, Fomboh CT, Cui L, Stresman G, Bigoga JD, Alifrangis M, Mbacham WF. Niba PTN, et al. Among authors: hocke ef. Int J Infect Dis. 2023 Jul;132:108-117. doi: 10.1016/j.ijid.2023.03.050. Epub 2023 Apr 6. Int J Infect Dis. 2023. PMID: 37028468 Free PMC article.
High DDT resistance without apparent association to kdr and Glutathione-S-transferase (GST) gene mutations in Aedes aegypti population at hotel compounds in Zanzibar.
Kampango A, Hocke EF, Hansson H, Furu P, Haji KA, David JP, Konradsen F, Saleh F, Weldon CW, Schiøler KL, Alifrangis M. Kampango A, et al. Among authors: hocke ef. PLoS Negl Trop Dis. 2022 May 16;16(5):e0010355. doi: 10.1371/journal.pntd.0010355. eCollection 2022 May. PLoS Negl Trop Dis. 2022. PMID: 35576233 Free PMC article.