Lau EK - Search Results

1

The functional role of L-fucose on dendritic cell function and polarization.

Burton C, Bitaraf A, Snyder K, Zhang C, Yoder SJ, Avram D, Du D, Yu X, Lau EK. Burton C, et al. Among authors: lau ek. Front Immunol. 2024 Apr 5;15:1353570. doi: 10.3389/fimmu.2024.1353570. eCollection 2024. Front Immunol. 2024. PMID: 38646527 Free PMC article.

2

Fucosylation of HLA-DRB1 regulates CD4⁺ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.

Lester DK, Burton C, Gardner A, Innamarato P, Kodumudi K, Liu Q, Adhikari E, Ming Q, Williamson DB, Frederick DT, Sharova T, White MG, Markowitz J, Cao B, Nguyen J, Johnson J, Beatty M, Mockabee-Macias A, Mercurio M, Watson G, Chen PL, McCarthy S, MoranSegura C, Messina J, Thomas KL, Darville L, Izumi V, Koomen JM, Pilon-Thomas SA, Ruffell B, Luca VC, Haltiwanger RS, Wang X, Wargo JA, Boland GM, Lau EK. Lester DK, et al. Among authors: lau ek. Nat Cancer. 2023 Feb;4(2):222-239. doi: 10.1038/s43018-022-00506-7. Epub 2023 Jan 23. Nat Cancer. 2023. PMID: 36690875 Free PMC article.

3

The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells.

Keeley T, Lin S, Lester DK, Lau EK, Yang S. Keeley T, et al. Among authors: lau ek. PLoS One. 2018 Jun 20;13(6):e0199128. doi: 10.1371/journal.pone.0199128. eCollection 2018. PLoS One. 2018. PMID: 29924834 Free PMC article.

4

The Diverse Contributions of Fucose Linkages in Cancer.

Keeley TS, Yang S, Lau E. Keeley TS, et al. Cancers (Basel). 2019 Aug 24;11(9):1241. doi: 10.3390/cancers11091241. Cancers (Basel). 2019. PMID: 31450600 Free PMC article. Review.

5

Brain metastasis-associated fibroblasts secrete fucosylated PVR/CD155 that induces breast cancer invasion.

Adhikari E, Liu Q, Johnson J, Stewart P, Marusyk V, Fang B, Izumi V, Bowers K, Guzman KM, Koomen JM, Marusyk A, Lau EK. Adhikari E, et al. Among authors: lau ek. Cell Rep. 2023 Dec 26;42(12):113463. doi: 10.1016/j.celrep.2023.113463. Epub 2023 Nov 22. Cell Rep. 2023. PMID: 37995180 Free article.

6

Androgen drives melanoma invasiveness and metastatic spread by inducing tumorigenic fucosylation.

Liu Q, Adhikari E, Lester DK, Fang B, Johnson JO, Tian Y, Mockabee-Macias AT, Izumi V, Guzman KM, White MG, Koomen JM, Wargo JA, Messina JL, Qi J, Lau EK. Liu Q, et al. Among authors: lau ek. Nat Commun. 2024 Feb 7;15(1):1148. doi: 10.1038/s41467-024-45324-w. Nat Commun. 2024. PMID: 38326303 Free PMC article.

7

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy.

Emmons MF, Faião-Flores F, Sharma R, Thapa R, Messina JL, Becker JC, Schadendorf D, Seto E, Sondak VK, Koomen JM, Chen YA, Lau EK, Wan L, Licht JD, Smalley KSM. Emmons MF, et al. Among authors: lau ek. Cancer Res. 2019 Jun 1;79(11):2947-2961. doi: 10.1158/0008-5472.CAN-19-0040. Epub 2019 Apr 15. Cancer Res. 2019. PMID: 30987999 Free PMC article.

8

The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression.

Vera O, Martinez M, Soto-Vargas Z, Wang K, Xu X, Ruiz-Buceta S, Mecozzi N, Chadourne M, Posorske B, Angarita A, Bok I, Liu Q, Murikipudi H, Kim Y, Messina JL, Tsai KY, Major MB, Lau EK, Yu X, Ibanez-de-Caceres I, Karreth FA. Vera O, et al. Among authors: lau ek. bioRxiv [Preprint]. 2024 Sep 6:2024.09.03.611024. doi: 10.1101/2024.09.03.611024. bioRxiv. 2024. PMID: 39282450 Free PMC article. Preprint.

9

NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis.

Ilter D, Drapela S, Schild T, Ward NP, Adhikari E, Low V, Asara J, Oskarsson T, Lau EK, DeNicola GM, McReynolds MR, Gomes AP. Ilter D, et al. Among authors: lau ek. Redox Biol. 2023 May;61:102627. doi: 10.1016/j.redox.2023.102627. Epub 2023 Feb 9. Redox Biol. 2023. PMID: 36841051 Free PMC article.

10

Structure of the planar cell polarity cadherins Fat4 and Dachsous1.

Medina E, Easa Y, Lester DK, Lau EK, Sprinzak D, Luca VC. Medina E, et al. Among authors: lau ek. Nat Commun. 2023 Feb 16;14(1):891. doi: 10.1038/s41467-023-36435-x. Nat Commun. 2023. PMID: 36797229 Free PMC article.

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