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Fatty acid β-oxidation in brain mitochondria: Insights from high-resolution respirometry in mouse, rat and Drosophila brain, ischemia and aging models.
Cardoso LHD, Cecatto C, Ozola M, Korzh S, Zvejniece L, Gukalova B, Doerrier C, Dambrova M, Makrecka-Kuka M, Gnaiger E, Liepinsh E. Cardoso LHD, et al. Among authors: ozola m. Biochim Biophys Acta Mol Basis Dis. 2025 Jan;1871(1):167544. doi: 10.1016/j.bbadis.2024.167544. Epub 2024 Oct 17. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39424161 Free article.
Development of Potent Microtubule Targeting Agent by Structural Simplification of Natural Diazonamide.
Kalnins T, Vitkovska V, Kazak M, Zelencova-Gopejenko D, Ozola M, Narvaiss N, Makrecka-Kuka M, Domračeva I, Kinens A, Gukalova B, Konrad N, Aav R, Bonato F, Lucena-Agell D, Díaz JF, Liepinsh E, Suna E. Kalnins T, et al. Among authors: ozola m. J Med Chem. 2024 Jun 13;67(11):9227-9259. doi: 10.1021/acs.jmedchem.4c00388. Epub 2024 Jun 4. J Med Chem. 2024. PMID: 38833507
Hydroxymethylglutaryl-CoA reductase activity is essential for mitochondrial β-oxidation of fatty acids to prevent lethal accumulation of long-chain acylcarnitines in the mouse liver.
Liepinsh E, Zvejniece L, Clemensson L, Ozola M, Vavers E, Cirule H, Korzh S, Skuja S, Groma V, Briviba M, Grinberga S, Liu W, Olszewski P, Gentreau M, Fredriksson R, Dambrova M, Schiöth HB. Liepinsh E, et al. Among authors: ozola m. Br J Pharmacol. 2024 Aug;181(16):2750-2773. doi: 10.1111/bph.16363. Epub 2024 Apr 19. Br J Pharmacol. 2024. PMID: 38641905