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Page 1
Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis.
Mocci G, Sukhavasi K, Örd T, Bankier S, Singha P, Arasu UT, Agbabiaje OO, Mäkinen P, Ma L, Hodonsky CJ, Aherrahrou R, Muhl L, Liu J, Gustafsson S, Byandelger B, Wang Y, Koplev S, Lendahl U, Owens GK, Leeper NJ, Pasterkamp G, Vanlandewijck M, Michoel T, Ruusalepp A, Hao K, Ylä-Herttuala S, Väli M, Järve H, Mokry M, Civelek M, Miller CJ, Kovacic JC, Kaikkonen MU, Betsholtz C, Björkegren JLM. Mocci G, et al. Among authors: sukhavasi k. Circ Res. 2024 May 24;134(11):1405-1423. doi: 10.1161/CIRCRESAHA.123.323184. Epub 2024 Apr 19. Circ Res. 2024. PMID: 38639096 Free PMC article.
Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence.
Savić R, Yang J, Koplev S, An MC, Patel PL, O'Brien RN, Dubose BN, Dodatko T, Rogatsky E, Sukhavasi K, Ermel R, Ruusalepp A, Houten SM, Kovacic JC, Stewart AF, Yohn CB, Schadt EE, Laberge RM, Björkegren JLM, Tu Z, Argmann C. Savić R, et al. Among authors: sukhavasi k. Cell Rep. 2023 Nov 28;42(11):113371. doi: 10.1016/j.celrep.2023.113371. Epub 2023 Nov 7. Cell Rep. 2023. PMID: 37938972 Free PMC article.
A mechanistic framework for cardiometabolic and coronary artery diseases.
Koplev S, Seldin M, Sukhavasi K, Ermel R, Pang S, Zeng L, Bankier S, Di Narzo A, Cheng H, Meda V, Ma A, Talukdar H, Cohain A, Amadori L, Argmann C, Houten SM, Franzén O, Mocci G, Meelu OA, Ishikawa K, Whatling C, Jain A, Jain RK, Gan LM, Giannarelli C, Roussos P, Hao K, Schunkert H, Michoel T, Ruusalepp A, Schadt EE, Kovacic JC, Lusis AJ, Björkegren JLM. Koplev S, et al. Among authors: sukhavasi k. Nat Cardiovasc Res. 2022 Jan;1(1):85-100. doi: 10.1038/s44161-021-00009-1. Epub 2022 Jan 12. Nat Cardiovasc Res. 2022. PMID: 36276926 Free PMC article.
The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1.
Ma L, Bryce NS, Turner AW, Di Narzo AF, Rahman K, Xu Y, Ermel R, Sukhavasi K, d'Escamard V, Chandel N, V'Gangula B, Wolhuter K, Kadian-Dodov D, Franzen O, Ruusalepp A, Hao K, Miller CL, Björkegren JLM, Kovacic JC. Ma L, et al. Among authors: sukhavasi k. PLoS Genet. 2022 Jun 17;18(6):e1010261. doi: 10.1371/journal.pgen.1010261. eCollection 2022 Jun. PLoS Genet. 2022. PMID: 35714152 Free PMC article.
Publisher Correction: Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.
Li L, Chen Z, von Scheidt M, Li S, Steiner A, Güldener U, Koplev S, Ma A, Hao K, Pan C, Lusis AJ, Pang S, Kessler T, Ermel R, Sukhavasi K, Ruusalepp A, Gagneur J, Erdmann J, Kovacic JC, Björkegren JLM, Schunkert H. Li L, et al. Among authors: sukhavasi k. Basic Res Cardiol. 2022 Apr 5;117(1):19. doi: 10.1007/s00395-022-00923-w. Basic Res Cardiol. 2022. PMID: 35381883 Free PMC article. No abstract available.
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes.
Li L, Chen Z, von Scheidt M, Li S, Steiner A, Güldener U, Koplev S, Ma A, Hao K, Pan C, Lusis AJ, Pang S, Kessler T, Ermel R, Sukhavasi K, Ruusalepp A, Gagneur J, Erdmann J, Kovacic JC, Björkegren JLM, Schunkert H. Li L, et al. Among authors: sukhavasi k. Basic Res Cardiol. 2022 Feb 17;117(1):6. doi: 10.1007/s00395-022-00917-8. Basic Res Cardiol. 2022. PMID: 35175464 Free PMC article.
Integrative Prioritization of Causal Genes for Coronary Artery Disease.
Hao K, Ermel R, Sukhavasi K, Cheng H, Ma L, Li L, Amadori L, Koplev S, Franzén O, d'Escamard V, Chandel N, Wolhuter K, Bryce NS, Venkata VRM, Miller CL, Ruusalepp A, Schunkert H, Björkegren JLM, Kovacic JC. Hao K, et al. Among authors: sukhavasi k. Circ Genom Precis Med. 2022 Feb;15(1):e003365. doi: 10.1161/CIRCGEN.121.003365. Epub 2021 Dec 28. Circ Genom Precis Med. 2022. PMID: 34961328 Free PMC article.
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease.
Cohain AT, Barrington WT, Jordan DM, Beckmann ND, Argmann CA, Houten SM, Charney AW, Ermel R, Sukhavasi K, Franzen O, Koplev S, Whatling C, Belbin GM, Yang J, Hao K, Kenny EE, Tu Z, Zhu J, Gan LM, Do R, Giannarelli C, Kovacic JC, Ruusalepp A, Lusis AJ, Bjorkegren JLM, Schadt EE. Cohain AT, et al. Among authors: sukhavasi k. Nat Commun. 2021 Jan 22;12(1):547. doi: 10.1038/s41467-020-20750-8. Nat Commun. 2021. PMID: 33483510 Free PMC article.
Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.
Crawford AA, Bankier S, Altmaier E, Barnes CLK, Clark DW, Ermel R, Friedrich N, van der Harst P, Joshi PK, Karhunen V, Lahti J, Mahajan A, Mangino M, Nethander M, Neumann A, Pietzner M, Sukhavasi K, Wang CA, Bakker SJL, Bjorkegren JLM, Campbell H, Eriksson J, Gieger C, Hayward C, Jarvelin MR, McLachlan S, Morris AP, Ohlsson C, Pennell CE, Price J, Rudan I, Ruusalepp A, Spector T, Tiemeier H, Völzke H, Wilson JF, Michoel T, Timpson NJ, Smith GD, Walker BR; CORtisol NETwork (CORNET) consortium. Crawford AA, et al. Among authors: sukhavasi k. J Hum Genet. 2021 Jun;66(6):625-636. doi: 10.1038/s10038-020-00895-6. Epub 2021 Jan 20. J Hum Genet. 2021. PMID: 33469137 Free PMC article.
16 results