Bow EW - Search Results

1

Low-Efficacy Mu Opioid Agonists as Candidate Analgesics: Effects of Novel C-9 Substituted Phenylmorphans on Pain-Depressed Behavior in Mice.

Santos EJ, Akbarali HI, Bow EW, Chambers DR, Gutman ES, Jacobson AE, Kang M, Lee YK, Lutz JA, Rice KC, Sulima A, Negus SS. Santos EJ, et al. Among authors: bow ew. J Pharmacol Exp Ther. 2024 Oct 18;391(2):138-151. doi: 10.1124/jpet.124.002153. J Pharmacol Exp Ther. 2024. PMID: 38637015 Free PMC article.

2

Role of efficacy as a determinant of locomotor activation by mu-opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR-selective phenylmorphans with high-to-low MOR efficacy.

Santos EJ, Nassehi N, Bow EW, Chambers DR, Gutman ES, Jacobson AE, Lutz JA, Marsh SA, Rice KC, Sulima A, Selley DE, Negus SS. Santos EJ, et al. Among authors: bow ew. Pharmacol Res Perspect. 2023 Aug;11(4):e01111. doi: 10.1002/prp2.1111. Pharmacol Res Perspect. 2023. PMID: 37381112 Free PMC article.

3

G-Protein biased opioid agonists: 3-hydroxy-N-phenethyl-5-phenylmorphans with three-carbon chain substituents at C9.

Gutman ES, Bow E, Li F, Sulima A, Kaska S, Crowley R, Prisinzano TE, Lee YS, Hassan SA, Imler GH, Deschamps JR, Jacobson AE, Rice KC. Gutman ES, et al. RSC Med Chem. 2020 Jun 12;11(8):896-904. doi: 10.1039/d0md00104j. eCollection 2020 Aug 1. RSC Med Chem. 2020. PMID: 33479684 Free PMC article.

4

Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans.

Lutz JA, Sulima A, Gutman ES, Bow EW, Luo D, Kaska S, Prisinzano TE, Paronis CA, Bergman J, Imler GH, Kerr AT, Jacobson AE, Rice KC. Lutz JA, et al. Among authors: bow ew. Molecules. 2023 Jun 15;28(12):4795. doi: 10.3390/molecules28124795. Molecules. 2023. PMID: 37375350 Free PMC article.

5

Novel Vaccine That Blunts Fentanyl Effects and Sequesters Ultrapotent Fentanyl Analogues.

Barrientos RC, Bow EW, Whalen C, Torres OB, Sulima A, Beck Z, Jacobson AE, Rice KC, Matyas GR. Barrientos RC, et al. Among authors: bow ew. Mol Pharm. 2020 Sep 8;17(9):3447-3460. doi: 10.1021/acs.molpharmaceut.0c00497. Epub 2020 Aug 13. Mol Pharm. 2020. PMID: 32787282 Free PMC article.

6

Novel Dual-Target μ-Opioid Receptor and Dopamine D₃ Receptor Ligands as Potential Nonaddictive Pharmacotherapeutics for Pain Management.

Bonifazi A, Battiti FO, Sanchez J, Zaidi SA, Bow E, Makarova M, Cao J, Shaik AB, Sulima A, Rice KC, Katritch V, Canals M, Lane JR, Newman AH. Bonifazi A, et al. J Med Chem. 2021 Jun 10;64(11):7778-7808. doi: 10.1021/acs.jmedchem.1c00611. Epub 2021 May 20. J Med Chem. 2021. PMID: 34011153 Free PMC article.

7

Bivalent Conjugate Vaccine Induces Dual Immunogenic Response That Attenuates Heroin and Fentanyl Effects in Mice.

Barrientos RC, Whalen C, Torres OB, Sulima A, Bow EW, Komla E, Beck Z, Jacobson AE, Rice KC, Matyas GR. Barrientos RC, et al. Among authors: bow ew. Bioconjug Chem. 2021 Nov 17;32(11):2295-2306. doi: 10.1021/acs.bioconjchem.1c00179. Epub 2021 Jun 2. Bioconjug Chem. 2021. PMID: 34076427 Free PMC article.

8

The Structure-Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation.

Bow EW, Rimoldi JM. Bow EW, et al. Perspect Medicin Chem. 2016 Jun 28;8:17-39. doi: 10.4137/PMC.S32171. eCollection 2016. Perspect Medicin Chem. 2016. PMID: 27398024 Free PMC article.

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