Liu TT - Search Results

1

Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing Colorectal Cancer Therapy via Synthetic Lethality with ATR Inhibitors.

Liu TT, Wang Q, Zhou Y, Ye B, Liu T, Yan L, Fan J, Xu J, Zhou Y, Xia Z, Deng X. Liu TT, et al. Among authors: liu t. J Med Chem. 2024 May 9;67(9):7620-7634. doi: 10.1021/acs.jmedchem.4c00454. Epub 2024 Apr 18. J Med Chem. 2024. PMID: 38634707

2

Reprogramming Energy Metabolism with Synthesized PDK Inhibitors Based on Dichloroacetate Derivatives and Targeted Delivery Systems for Enhanced Cancer Therapy.

She W, Liu T, Li H, Wang Z, Guo Z, Liu Y, Liu Y. She W, et al. J Med Chem. 2023 Nov 9;66(21):14683-14699. doi: 10.1021/acs.jmedchem.3c01197. Epub 2023 Sep 9. J Med Chem. 2023. PMID: 37688544

3

Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer.

Wang Y, Wang C, Liu T, Qi H, Chen S, Cai X, Zhang M, Aliper A, Ren F, Ding X, Zhavoronkov A. Wang Y, et al. J Med Chem. 2024 Jan 11;67(1):420-432. doi: 10.1021/acs.jmedchem.3c01476. Epub 2023 Dec 26. J Med Chem. 2024. PMID: 38146659

4

Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer.

Wang C, Wang Y, Meng F, Liu T, Wang X, Cai X, Zhang M, Aliper A, Ren F, Zhavoronkov A, Ding X. Wang C, et al. Eur J Med Chem. 2025 Jan 5;281:117025. doi: 10.1016/j.ejmech.2024.117025. Epub 2024 Nov 5. Eur J Med Chem. 2025. PMID: 39515174

5

Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models.

Zhu W, Liu X, Li Q, Gao F, Liu T, Chen X, Zhang M, Aliper A, Ren F, Ding X, Zhavoronkov A. Zhu W, et al. Bioorg Med Chem. 2023 Aug 15;91:117414. doi: 10.1016/j.bmc.2023.117414. Epub 2023 Jul 13. Bioorg Med Chem. 2023. PMID: 37467565

6

Neuroprotective potential of isofraxidin: Alleviating parkinsonian symptoms, inflammation and microglial activation.

Wang TA, Li SY, Fann LY, Li IH, Liu TT, Hung HY, Chang CW, Cheng CC, Huang YC, Yu PY, Shih JH. Wang TA, et al. Among authors: liu tt. J Cent Nerv Syst Dis. 2025 Jan 9;17:11795735241312661. doi: 10.1177/11795735241312661. eCollection 2025. J Cent Nerv Syst Dis. 2025. PMID: 39790641 Free PMC article.

7

Functionalities of Tremella fuciformis Polysaccharides Modified with Gallic Acid.

Liu TT, Hong KS, Yang TS. Liu TT, et al. Molecules. 2024 Dec 13;29(24):5890. doi: 10.3390/molecules29245890. Molecules. 2024. PMID: 39769979 Free PMC article.

8

Integrating melt electrospinning writing and microfluidics to engineer a human cardiac microenvironment for high-fidelity drug screening.

Wang YH, Liu TT, Guo YP, Zhu SJ, Liao ZM, Song JM, Zhu XM, Liang JL, Nasser MI, Liu NB, Chang DH, Zhu P, Yao B. Wang YH, et al. Among authors: liu tt. Bioact Mater. 2024 Dec 11;45:551-566. doi: 10.1016/j.bioactmat.2024.11.037. eCollection 2025 Mar. Bioact Mater. 2024. PMID: 39759533 Free PMC article.

9

Exploring the Regulatory Mechanism of CXCL16 Molecule-Related Antigen Presentation Using lncRNA-mRNA Co-Expression Network Analysis.

Liu TT, Zheng S, Jia LX, Du J, Piao C. Liu TT, et al. J Inflamm Res. 2024 Dec 24;17:11561-11575. doi: 10.2147/JIR.S496133. eCollection 2024. J Inflamm Res. 2024. PMID: 39735899 Free PMC article.

10

Cross-sectional and longitudinal changes in category-selectivity in visual cortex following pediatric cortical resection.

Liu TT, Granovetter MC, Maallo AMS, Robert S, Fu JZ, Patterson C, Plaut DC, Behrmann M. Liu TT, et al. bioRxiv [Preprint]. 2024 Dec 12:2024.12.08.627367. doi: 10.1101/2024.12.08.627367. bioRxiv. 2024. PMID: 39713452 Free PMC article. Preprint.

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