Fan J - Search Results

1

Discovery of a Meisoindigo-Derived PROTAC as the ATM Degrader: Revolutionizing Colorectal Cancer Therapy via Synthetic Lethality with ATR Inhibitors.

Liu TT, Wang Q, Zhou Y, Ye B, Liu T, Yan L, Fan J, Xu J, Zhou Y, Xia Z, Deng X. Liu TT, et al. Among authors: fan j. J Med Chem. 2024 May 9;67(9):7620-7634. doi: 10.1021/acs.jmedchem.4c00454. Epub 2024 Apr 18. J Med Chem. 2024. PMID: 38634707

2

Access to 3a-Benzoylmethyl Pyrrolidino[2,3- b]indolines via Cu^II-Catalyzed Radical Annulation/C3-Functionalization Sequence.

Chen X, Fan J, Zeng G, Ma J, Wang C, Wang Y, Zhou Y, Deng X. Chen X, et al. Among authors: fan j. J Org Chem. 2018 Aug 3;83(15):8322-8330. doi: 10.1021/acs.joc.8b01017. Epub 2018 Jul 5. J Org Chem. 2018. PMID: 29925228

3

Dual-targeting Rutaecarpine-NO donor hybrids as novel anti-hypertensive agents by promoting release of CGRP.

Ma J, Chen L, Fan J, Cao W, Zeng G, Wang Y, Li Y, Zhou Y, Deng X. Ma J, et al. Among authors: fan j. Eur J Med Chem. 2019 Apr 15;168:146-153. doi: 10.1016/j.ejmech.2019.02.037. Epub 2019 Feb 18. Eur J Med Chem. 2019. PMID: 30818175

4

Divergent Reactivity in Cu^II-Catalyzed Oxidative Coupling between Indole/Tryptamine Derivatives and β-Arylacrylic Acids.

Cao W, Fan J, Yan L, Zeng G, Ma J, Wang Y, Zhou Y, Deng X. Cao W, et al. Among authors: fan j. Org Lett. 2019 Dec 6;21(23):9506-9511. doi: 10.1021/acs.orglett.9b03697. Epub 2019 Nov 20. Org Lett. 2019. PMID: 31747294

5

Development of Strigolactones as Novel Autophagy/Mitophagy Inhibitors against Colorectal Cancer Cells by Blocking the Autophagosome-Lysosome Fusion.

Yang ST, Fan JB, Liu TT, Ning S, Xu JH, Zhou YJ, Deng X. Yang ST, et al. J Med Chem. 2022 Jul 19. doi: 10.1021/acs.jmedchem.2c00275. Online ahead of print. J Med Chem. 2022. PMID: 35852796

6

Acid-promoted intra- and intermolecular [2+2] cycloaddition of indoles to aryl alkynes to access cyclobutene-fused indolines.

Wang Q, Wang SL, Fan JB, Zeng GY, Zhou YJ, Deng X. Wang Q, et al. Chem Commun (Camb). 2022 Aug 16;58(66):9270-9273. doi: 10.1039/d2cc02840a. Chem Commun (Camb). 2022. PMID: 35903993

7

Divergent synthesis of bis(indolyl)methanes via Fe^III-catalysed regioselective dehydrogenative coupling reactions: a biomimetic approach to 6,6'-bis-(debromo)-gelliusine F.

Wu Y, Liu MD, Wang Q, Tian H, Fan JB, Zhou YJ, Wang YJ, Deng X. Wu Y, et al. Org Biomol Chem. 2023 Jan 18;21(3):639-643. doi: 10.1039/d2ob02236b. Org Biomol Chem. 2023. PMID: 36562387

8

Rapid access to icetexane diterpenes: Their protective effects against lipopolysaccharides-induced acute lung injury via PI3K/AKT/NF-κB axis in macrophages.

Liu M, Tang Q, Wang Q, Xie W, Fan J, Tang S, Liu W, Zhou Y, Deng X. Liu M, et al. Among authors: fan j. Eur J Med Chem. 2023 Nov 15;260:115769. doi: 10.1016/j.ejmech.2023.115769. Epub 2023 Sep 1. Eur J Med Chem. 2023. PMID: 37683363

9

Discovery of meisoindigo derivatives as noncovalent and orally available M^pro inhibitors: their therapeutic implications in the treatment of COVID-19.

Gao Q, Liu S, Zhou Y, Fan J, Ke S, Zhou Y, Fan K, Wang Y, Zhou Y, Xia Z, Deng X. Gao Q, et al. Among authors: fan k, fan j. Eur J Med Chem. 2024 Jul 5;273:116498. doi: 10.1016/j.ejmech.2024.116498. Epub 2024 May 16. Eur J Med Chem. 2024. PMID: 38762916

10

Expanding horizons of iminosugars as broad-spectrum anti-virals: mechanism, efficacy and novel developments.

Liu Q, Liu Y, Liu T, Fan J, Xia Z, Zhou Y, Deng X. Liu Q, et al. Among authors: fan j. Nat Prod Bioprospect. 2024 Sep 26;14(1):55. doi: 10.1007/s13659-024-00477-5. Nat Prod Bioprospect. 2024. PMID: 39325109 Free PMC article. Review.

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