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Page 1
hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
Mambwe D, Coertzen D, Leshabane M, Mulubwa M, Njoroge M, Gibhard L, Girling G, Wicht KJ, Lee MCS, Wittlin S, Moreira DRM, Birkholtz LM, Chibale K. Mambwe D, et al. Among authors: girling g. ACS Med Chem Lett. 2024 Mar 18;15(4):463-469. doi: 10.1021/acsmedchemlett.3c00496. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628794 Free PMC article.
A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways.
Campino S, Marin-Menendez A, Kemp A, Cross N, Drought L, Otto TD, Benavente ED, Ravenhall M, Schwach F, Girling G, Manske M, Theron M, Gould K, Drury E, Clark TG, Kwiatkowski DP, Pance A, Rayner JC. Campino S, et al. Among authors: girling g. PLoS Pathog. 2018 Nov 29;14(11):e1007436. doi: 10.1371/journal.ppat.1007436. eCollection 2018 Nov. PLoS Pathog. 2018. PMID: 30496294 Free PMC article.
Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Bushell E, Gomes AR, Sanderson T, Anar B, Girling G, Herd C, Metcalf T, Modrzynska K, Schwach F, Martin RE, Mather MW, McFadden GI, Parts L, Rutledge GG, Vaidya AB, Wengelnik K, Rayner JC, Billker O. Bushell E, et al. Among authors: girling g. Cell. 2017 Jul 13;170(2):260-272.e8. doi: 10.1016/j.cell.2017.06.030. Cell. 2017. PMID: 28708996 Free PMC article.
An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi.
Marr EJ, Milne RM, Anar B, Girling G, Schwach F, Mooney JP, Nahrendorf W, Spence PJ, Cunningham D, Baker DA, Langhorne J, Rayner JC, Billker O, Bushell ES, Thompson J. Marr EJ, et al. Among authors: girling g. Wellcome Open Res. 2020 Jun 24;5:71. doi: 10.12688/wellcomeopenres.15587.2. eCollection 2020. Wellcome Open Res. 2020. PMID: 32500098 Free PMC article.
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations.
Pallaseni A, Peets EM, Girling G, Crepaldi L, Kuzmin I, Moor M, Muñoz-Subirana N, Schimmel J, Serçin Ö, Mardin BR, Tijsterman M, Peterson H, Kosicki M, Parts L. Pallaseni A, et al. Among authors: girling g. bioRxiv [Preprint]. 2024 Sep 14:2023.06.28.546891. doi: 10.1101/2023.06.28.546891. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 27;15(1):10271. doi: 10.1038/s41467-024-54566-7. PMID: 37425722 Free PMC article. Updated. Preprint.
Randomizing the human genome by engineering recombination between repeat elements.
Koeppel J, Ferreira R, Vanderstichele T, Riedmayr LM, Peets EM, Girling G, Weller J, Murat P, Liberante FG, Ellis T, Church GM, Parts L. Koeppel J, et al. Among authors: girling g. Science. 2025 Jan 31;387(6733):eado3979. doi: 10.1126/science.ado3979. Epub 2025 Jan 31. Science. 2025. PMID: 39883775
17 results