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Page 1
Intention-to-treat outcomes utilising a stringent event definition in children and young people treated with tisagenlecleucel for r/r ALL through a national access scheme.
Oporto Espuelas M, Burridge S, Kirkwood AA, Bonney D, Watts K, Shenton G, Jalowiec KA, O'Reilly MA, Roddie C, Castleton A, Clesham K, Nicholson E, Alajangi R, Prabhu S, George L, Uttenthal B, Gabelli M, Neill L, Besley C, Chaganti S, Wynn RF, Bartram J, Chiesa R, Lucchini G, Pavasovic V, Rao A, Rao K, Silva J, Samarasinghe S, Vora A, Clark P, Cummins M, Marks DI, Amrolia P, Hough R, Ghorashian S. Oporto Espuelas M, et al. Among authors: shenton g. Blood Cancer J. 2024 Apr 15;14(1):66. doi: 10.1038/s41408-024-01038-2. Blood Cancer J. 2024. PMID: 38622139 Free PMC article.
UK experience of unrelated cord blood transplantation in paediatric patients.
Veys P, Danby R, Vora A, Slatter M, Wynn R, Lawson S, Steward C, Gibson B, Potter M, de la Fuente J, Shenton G, Cornish J, Gennery A, Snowden JA, Bonney D, Velangi M, Ruggeri A, Gluckman E, Hough R, Rocha V; British Society of Blood and Marrow Transplantation and Eurocord. Veys P, et al. Among authors: shenton g. Br J Haematol. 2016 Feb;172(3):482-6. doi: 10.1111/bjh.13914. Epub 2016 Jan 5. Br J Haematol. 2016. PMID: 26728432 Free article. No abstract available.
Tisagenlecleucel therapy for relapsed or refractory B-cell acute lymphoblastic leukaemia in infants and children younger than 3 years of age at screening: an international, multicentre, retrospective cohort study.
Ghorashian S, Jacoby E, De Moerloose B, Rives S, Bonney D, Shenton G, Bader P, Bodmer N, Quintana AM, Herrero B, Algeri M, Locatelli F, Vettenranta K, Gonzalez B, Attarbaschi A, Harris S, Bourquin JP, Baruchel A. Ghorashian S, et al. Among authors: shenton g. Lancet Haematol. 2022 Oct;9(10):e766-e775. doi: 10.1016/S2352-3026(22)00225-3. Epub 2022 Sep 6. Lancet Haematol. 2022. PMID: 36084658 Free article.
Alemtuzumab, Dual Graft-versus-Host Disease Prophylaxis, and Lower CD3+ T Cell Doses Equalize Rates of Acute and Chronic Graft-versus-Host Disease in Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation with Matched Unrelated Donor Peripheral Blood Stem Cells or Bone Marrow Grafts.
Lum SH, James B, Ottaviano G, Ewins AM, Patrick K, Ali S, Carpenter B, Silva J, Tewari S, Furness C, Thomas A, Shenton G, Bonney D, Moppett J, Hambleton S, Gennery AR, Amrolia P, Gibson B, Hough R, Rao K, Slatter M, Wynn R. Lum SH, et al. Among authors: shenton g. Transplant Cell Ther. 2024 Mar;30(3):314.e1-314.e12. doi: 10.1016/j.jtct.2023.12.005. Epub 2023 Dec 14. Transplant Cell Ther. 2024. PMID: 38103787 Free article.
CD3+TCRαβ/CD19+-depleted stem cell boost and CD45RO+ memory T-cell add-back as a successful salvage treatment for poor graft function unresponsive to eltrombopag, following a second allogenic HSCT.
Ramanathan S, Roberts W, Nademi Z, Shenton G, Watson H, Matthews E, Carruthers K, Gennery AR, Hambleton S, Slatter M, Lum SH. Ramanathan S, et al. Among authors: shenton g. Pediatr Blood Cancer. 2024 Oct;71(10):e31203. doi: 10.1002/pbc.31203. Epub 2024 Jul 15. Pediatr Blood Cancer. 2024. PMID: 39010278 No abstract available.
Allogenic haematopoeitic stem cell transplant as cure for severe transfusion-dependent non-dominant hereditary spherocytosis due to homozygous SPTA1 mutation.
Ramanathan S, Roberts W, Carey P, Marshall S, Shenton G, Munoz-Diaz M, Biss T, Skinner R, Fuente J, Slatter M, Lum SH. Ramanathan S, et al. Among authors: shenton g. Pediatr Blood Cancer. 2023 Feb;70(2):e29928. doi: 10.1002/pbc.29928. Epub 2022 Aug 11. Pediatr Blood Cancer. 2023. PMID: 35950897 No abstract available.
Selumetinib in combination with dexamethasone for the treatment of relapsed/refractory RAS-pathway mutated paediatric and adult acute lymphoblastic leukaemia (SeluDex): study protocol for an international, parallel-group, dose-finding with expansion phase I/II trial.
Menne T, Slade D, Savage J, Johnson S, Irving J, Kearns P, Plummer R, Shenton G, Veal GJ, Vormoor B, Vormoor J, Billingham L. Menne T, et al. Among authors: shenton g. BMJ Open. 2022 Mar 4;12(3):e059872. doi: 10.1136/bmjopen-2021-059872. BMJ Open. 2022. PMID: 35246426 Free PMC article.
27 results