Zhang GT - Search Results

1

Small molecule deoxynyboquinone triggers alkylation and ubiquitination of Keap1 at Cys489 on Kelch domain for Nrf2 activation and inflammatory therapy.

Linghu KG, Zhang T, Zhang GT, Lv P, Zhang WJ, Zhao GD, Xiong SH, Ma QS, Zhao MM, Chen M, Hu YJ, Zhang CS, Yu H. Linghu KG, et al. Among authors: zhang gt. J Pharm Anal. 2024 Mar;14(3):401-415. doi: 10.1016/j.jpha.2023.07.009. Epub 2023 Jul 17. J Pharm Anal. 2024. PMID: 38618249 Free PMC article.

2

Recent Advances in Discovery, Biosynthesis and Genome Mining of Medicinally Relevant Polycyclic Tetramate Macrolactams.

Zhang G, Zhang W, Saha S, Zhang C. Zhang G, et al. Curr Top Med Chem. 2016;16(15):1727-39. doi: 10.2174/1568026616666151012112818. Curr Top Med Chem. 2016. PMID: 26456464 Review.

3

Engineered Biosynthesis of 5/5/6 Type Polycyclic Tetramate Macrolactams in an Ikarugamycin (5/6/5 Type)-Producing Chassis.

Jin H, Zhang W, Zhang G, Zhang L, Liu W, Zhang C. Jin H, et al. Org Lett. 2020 Mar 6;22(5):1731-1735. doi: 10.1021/acs.orglett.9b04672. Epub 2020 Feb 13. Org Lett. 2020. PMID: 32052979

4

A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.

Jiang P, Jin H, Zhang G, Zhang W, Liu W, Zhu Y, Zhang C, Zhang L. Jiang P, et al. Angew Chem Int Ed Engl. 2023 Dec 18;62(51):e202310728. doi: 10.1002/anie.202310728. Epub 2023 Nov 14. Angew Chem Int Ed Engl. 2023. PMID: 37917570

5

Deciphering Deoxynybomycin Biosynthesis Reveals Fe(II)/α-Ketoglutarate-Dependent Dioxygenase-Catalyzed Oxazoline Ring Formation and Decomposition.

Liu K, Zhang J, Zhang G, Zhang L, Meng Z, Ma L, Zhang W, Xiong W, Zhu Y, Wang B, Zhang C. Liu K, et al. J Am Chem Soc. 2023 Dec 20;145(50):27886-27899. doi: 10.1021/jacs.3c11772. Epub 2023 Dec 6. J Am Chem Soc. 2023. PMID: 38055632

6

Cylindromicin from Arctic-Derived Fungus Tolypocladium sp. SCSIO 40433.

Khan I, Peng J, Fang Z, Liu W, Zhang W, Zhang Q, Ma L, Zhang G, Zhang C, Zhang H. Khan I, et al. Molecules. 2021 Feb 18;26(4):1080. doi: 10.3390/molecules26041080. Molecules. 2021. PMID: 33670784 Free PMC article.

7

Mechanistic insights into polycycle formation by reductive cyclization in ikarugamycin biosynthesis.

Zhang G, Zhang W, Zhang Q, Shi T, Ma L, Zhu Y, Li S, Zhang H, Zhao YL, Shi R, Zhang C. Zhang G, et al. Angew Chem Int Ed Engl. 2014 May 5;53(19):4840-4. doi: 10.1002/anie.201402078. Epub 2014 Apr 6. Angew Chem Int Ed Engl. 2014. PMID: 24706593

8

Characterization of Heronamide Biosynthesis Reveals a Tailoring Hydroxylase and Indicates Migrated Double Bonds.

Zhu Y, Zhang W, Chen Y, Yuan C, Zhang H, Zhang G, Ma L, Zhang Q, Tian X, Zhang S, Zhang C. Zhu Y, et al. Chembiochem. 2015 Sep 21;16(14):2086-93. doi: 10.1002/cbic.201500281. Epub 2015 Aug 6. Chembiochem. 2015. PMID: 26194087

9

Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032.

Ma L, Zhang W, Zhu Y, Zhang G, Zhang H, Zhang Q, Zhang L, Yuan C, Zhang C. Ma L, et al. Appl Microbiol Biotechnol. 2017 Aug;101(15):6123-6136. doi: 10.1007/s00253-017-8375-5. Epub 2017 Jun 15. Appl Microbiol Biotechnol. 2017. PMID: 28620687

10

Host-dependent heterologous expression of berninamycin gene cluster leads to linear thiopeptide antibiotics.

De BC, Zhang W, Zhang G, Liu Z, Tan B, Zhang Q, Zhang L, Zhang H, Zhu Y, Zhang C. De BC, et al. Org Biomol Chem. 2021 Oct 27;19(41):8940-8946. doi: 10.1039/d1ob01759d. Org Biomol Chem. 2021. PMID: 34617948

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