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Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration.
Saito-Diaz K, Dietrich P, Saini T, Rashid MM, Wu HF, Ishan M, Sun X, Bedillion S, Patel AJ, Prudden AR, Wzientek CG, Knight TN, Chen YW, Boons GJ, Chen S, Studer L, Tiemeyer M, Xu B, Dragatsis I, Liu HX, Zeltner N. Saito-Diaz K, et al. Sci Transl Med. 2024 Nov 20;16(774):eadq2418. doi: 10.1126/scitranslmed.adq2418. Epub 2024 Nov 20. Sci Transl Med. 2024. PMID: 39565876
Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development.
Wu HF, Saito-Diaz K, Huang CW, McAlpine JL, Seo DE, Magruder DS, Ishan M, Bergeron HC, Delaney WH, Santori FR, Krishnaswamy S, Hart GW, Chen YW, Hogan RJ, Liu HX, Ivanova NB, Zeltner N. Wu HF, et al. Among authors: saito diaz k. Cell Stem Cell. 2024 May 2;31(5):734-753.e8. doi: 10.1016/j.stem.2024.03.011. Epub 2024 Apr 11. Cell Stem Cell. 2024. PMID: 38608707
Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.
Saito-Diaz K, Dietrich P, Wu HF, Sun X, Patel AJ, Wzientek CG, Prudden AR, Boons GJ, Chen S, Studer L, Xu B, Dragatsis I, Zeltner N. Saito-Diaz K, et al. bioRxiv [Preprint]. 2023 Mar 24:2023.03.22.533831. doi: 10.1101/2023.03.22.533831. bioRxiv. 2023. Update in: Sci Transl Med. 2024 Nov 20;16(774):eadq2418. doi: 10.1126/scitranslmed.adq2418 PMID: 36993570 Free PMC article. Updated. Preprint.
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Among authors: saito diaz k. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
19 results