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Page 1
EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening.
Cappelletto A, Alfì E, Volf N, Vu TVA, Bortolotti F, Ciucci G, Vodret S, Fantuz M, Perin M, Colliva A, Rozzi G, Rossi M, Ruozi G, Zentilin L, Vuerich R, Borin D, Lapasin R, Piazza S, Chiesa M, Lorizio D, Triboli L, Kumar S, Morello G, Tripodo C, Pinamonti M, Piperno GM, Benvenuti F, Rustighi A, Jo H, Piccolo S, Del Sal G, Carrer A, Giacca M, Zacchigna S. Cappelletto A, et al. Among authors: piperno gm. J Exp Clin Cancer Res. 2024 Jan 10;43(1):15. doi: 10.1186/s13046-023-02942-4. J Exp Clin Cancer Res. 2024. PMID: 38195652 Free PMC article.
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.
López L, Morosi LG, La Terza F, Bourdely P, Rospo G, Amadio R, Piperno GM, Russo V, Volponi C, Vodret S, Joshi S, Giannese F, Lazarevic D, Germano G, Stoitzner P, Bardelli A, Dalod M, Pace L, Caronni N, Guermonprez P, Benvenuti F. López L, et al. Among authors: piperno gm. Nat Commun. 2024 Mar 13;15(1):2280. doi: 10.1038/s41467-024-46685-y. Nat Commun. 2024. PMID: 38480738 Free PMC article.
A mitochondrial quality control mechanism reverses the phagosome maturation arrest caused by Mycobacterium tuberculosis.
Verma S, Das M, Sharma RD, Yadav V, Thakur S, Sharma P, Marzuki M, Foo S, Piperno GM, Khan MZ, Mathew B, Bajpai M, Maras JS, Howland S, Sarkar S, Benvenuti F, Singh A, Nandicoori V, Singhal A, Kumar D. Verma S, et al. Among authors: piperno gm. bioRxiv [Preprint]. 2023 Dec 1:2023.12.01.569475. doi: 10.1101/2023.12.01.569475. bioRxiv. 2023. PMID: 38076943 Free PMC article. Preprint.
CXCL5-mediated accumulation of mature neutrophils in lung cancer tissues impairs the differentiation program of anticancer CD8 T cells and limits the efficacy of checkpoint inhibitors.
Simoncello F, Piperno GM, Caronni N, Amadio R, Cappelletto A, Canarutto G, Piazza S, Bicciato S, Benvenuti F. Simoncello F, et al. Among authors: piperno gm. Oncoimmunology. 2022 Apr 7;11(1):2059876. doi: 10.1080/2162402X.2022.2059876. eCollection 2022. Oncoimmunology. 2022. PMID: 35402081 Free PMC article.
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses.
Caronni N, Piperno GM, Simoncello F, Romano O, Vodret S, Yanagihashi Y, Dress R, Dutertre CA, Bugatti M, Bourdeley P, Del Prete A, Schioppa T, Mazza EMC, Collavin L, Zacchigna S, Ostuni R, Guermonprez P, Vermi W, Ginhoux F, Bicciato S, Nagata S, Benvenuti F. Caronni N, et al. Among authors: piperno gm. Nat Commun. 2021 Apr 14;12(1):2237. doi: 10.1038/s41467-021-22535-z. Nat Commun. 2021. PMID: 33854047 Free PMC article.
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