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Page 1
SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner.
Saccon TD, Mousovich-Neto F, Ludwig RG, Carregari VC, Dos Anjos Souza AB, Dos Passos ASC, Martini MC, Barbosa PP, de Souza GF, Muraro SP, Forato J, Amorim MR, Marques RE, Veras FP, Barreto E, Gonçalves TT, Paiva IM, Fazolini NPB, Onodera CMK, Martins Junior RB, de Araújo PHC, Batah SS, Viana RMM, de Melo DM, Fabro AT, Arruda E, Queiroz Cunha F, Cunha TM, Pretti MAM, Smith BJ, Marques-Souza H, Knittel TL, Ruiz GP, Profeta GS, Fontes-Cal TCM, Boroni M, Vinolo MAR, Farias AS, Moraes-Vieira PMM, Bizzacchi JMA, Teesalu T, Chaim FDM, Cazzo E, Chaim EA, Proença-Módena JL, Martins-de-Souza D, Osako MK, Leiria LO, Mori MA. Saccon TD, et al. Among authors: ludwig rg. Nat Commun. 2022 Sep 29;13(1):5722. doi: 10.1038/s41467-022-33218-8. Nat Commun. 2022. PMID: 36175400 Free PMC article.
A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Tan D, et al. Among authors: ludwig rg. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266352 Free PMC article.
SARS-CoV-2 uses CD4 to infect T helper lymphocytes.
Brunetti NS, Davanzo GG, de Moraes D, Ferrari AJR, Souza GF, Muraro SP, Knittel TL, Boldrini VO, Monteiro LB, Virgílio-da-Silva JV, Profeta GS, Wassano NS, Nunes Santos L, Carregari VC, Dias AHS, Veras FP, Tavares LA, Forato J, Castro IMS, Silva-Costa LC, Palma AC, Mansour E, Ulaf RG, Bernardes AF, Nunes TA, Ribeiro LC, Agrela MV, Moretti ML, Buscaratti LI, Crunfli F, Ludwig RG, Gerhardt JA, Munhoz-Alves N, Marques AM, Sesti-Costa R, Amorim MR, Toledo-Teixeira DA, Parise PL, Martini MC, Bispos-Dos-Santos K, Simeoni CL, Granja F, Silvestrini VC, de Oliveira EB, Faca VM, Carvalho M, Castelucci BG, Pereira AB, Coimbra LD, Dias MMG, Rodrigues PB, Gomes ABSP, Pereira FB, Santos LMB, Bloyet LM, Stumpf S, Pontelli MC, Whelan S, Sposito AC, Carvalho RF, Vieira AS, Vinolo MAR, Damasio A, Velloso L, Figueira ACM, da Silva LLP, Cunha TM, Nakaya HI, Marques-Souza H, Marques RE, Martins-de-Souza D, Skaf MS, Proenca-Modena JL, Moraes-Vieira PMM, Mori MA, Farias AS. Brunetti NS, et al. Among authors: ludwig rg. Elife. 2023 Jul 31;12:e84790. doi: 10.7554/eLife.84790. Elife. 2023. PMID: 37523305 Free PMC article.
Diving into the proteomic atlas of SARS-CoV-2 infected cells.
Carregari VC, Reis-de-Oliveira G, Crunfli F, Smith BJ, de Souza GF, Muraro SP, Saia-Cereda VM, Vendramini PH, Baldasso PA, Silva-Costa LC, Zuccoli GS, Brandão-Teles C, Antunes A, Valença AF, Davanzo GG, Virgillio-da-Silva JV, Dos Reis Araújo T, Guimarães RC, Chaim FDM, Chaim EA, Kawagosi Onodera CM, Ludwig RG, Saccon TD, Damásio ARL, Leiria LOS, Vinolo MAR, Farias AS, Moraes-Vieira PM, Mori MA, Módena JLP, Martins-de-Souza D. Carregari VC, et al. Among authors: ludwig rg. Sci Rep. 2024 Mar 28;14(1):7375. doi: 10.1038/s41598-024-56328-3. Sci Rep. 2024. PMID: 38548777 Free PMC article.
Metformin acts in the gut and induces gut-liver crosstalk.
Tobar N, Rocha GZ, Santos A, Guadagnini D, Assalin HB, Camargo JA, Gonçalves AESS, Pallis FR, Oliveira AG, Rocco SA, Neto RM, de Sousa IL, Alborghetti MR, Sforça ML, Rodrigues PB, Ludwig RG, Vanzela EC, Brunetto SQ, Boer PA, Gontijo JAR, Geloneze B, Carvalho CRO, Prada PO, Folli F, Curi R, Mori MA, Vinolo MAR, Ramos CD, Franchini KG, Tormena CF, Saad MJA. Tobar N, et al. Among authors: ludwig rg. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2211933120. doi: 10.1073/pnas.2211933120. Epub 2023 Jan 19. Proc Natl Acad Sci U S A. 2023. PMID: 36656866 Free PMC article.
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