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Insights into pharmacogenetics, drug-gene interactions, and drug-drug-gene interactions.
Drug Metab Rev. 2024 Aug 18:1-19. doi: 10.1080/03602532.2024.2385928. Online ahead of print.
Drug Metab Rev. 2024.
PMID: 39154360
Review.
Enzyme-mediated drug-drug interactions: a review of in vivo and in vitro methodologies, regulatory guidance, and translation to the clinic.
Yadav J, Maldonato BJ, Roesner JM, Vergara AG, Paragas EM, Aliwarga T, Humphreys S.
Yadav J, et al. Among authors: maldonato bj.
Drug Metab Rev. 2024 Jul 26:1-33. doi: 10.1080/03602532.2024.2381021. Online ahead of print.
Drug Metab Rev. 2024.
PMID: 39057923
Review.
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Transporter-mediated drug-drug interactions: regulatory guidelines, in vitro and in vivo methodologies and translation, special populations, and the blood-brain barrier.
Russell LE, Yadav J, Maldonato BJ, Chien HC, Zou L, Vergara AG, Villavicencio EG.
Russell LE, et al. Among authors: maldonato bj.
Drug Metab Rev. 2024 Jul 5:1-28. doi: 10.1080/03602532.2024.2364591. Online ahead of print.
Drug Metab Rev. 2024.
PMID: 38967415
Review.
Item in Clipboard
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Jiang J, Jiang L, Maldonato BJ, Wang Y, Holderfield M, Aronchik I, Winters IP, Salman Z, Blaj C, Menard M, Brodbeck J, Chen Z, Wei X, Rosen MJ, Gindin Y, Lee BJ, Evans JW, Chang S, Wang Z, Seamon KJ, Parsons D, Cregg J, Marquez A, Tomlinson ACA, Yano JK, Knox JE, Quintana E, Aguirre AJ, Arbour KC, Reed A, Gustafson WC, Gill AL, Koltun ES, Wildes D, Smith JAM, Wang Z, Singh M.
Jiang J, et al. Among authors: maldonato bj.
Cancer Discov. 2024 Jun 3;14(6):994-1017. doi: 10.1158/2159-8290.CD-24-0027.
Cancer Discov. 2024.
PMID: 38593348
Free PMC article.
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METTL7A (TMT1A) and METTL7B (TMT1B) Are Responsible for Alkyl S-Thiol Methyl Transferase Activity in Liver.
Russell DA, Chau MK, Shi Y, Levasseur IN, Maldonato BJ, Totah RA.
Russell DA, et al. Among authors: maldonato bj.
Drug Metab Dispos. 2023 Aug;51(8):1024-1034. doi: 10.1124/dmd.123.001268. Epub 2023 May 3.
Drug Metab Dispos. 2023.
PMID: 37137720
Free PMC article.
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Epigenetics in drug disposition & drug therapy: symposium report of the 24th North American meeting of the International Society for the Study of Xenobiotics (ISSX).
Maldonato BJ, Vergara AG, Yadav J, Glass SM, Paragas EM, Li D, Lazarus P, McClay JL, Ning B, Daly AK, Russell LE.
Maldonato BJ, et al.
Drug Metab Rev. 2022 Aug;54(3):318-330. doi: 10.1080/03602532.2022.2101662. Epub 2022 Aug 24.
Drug Metab Rev. 2022.
PMID: 35876105
Free PMC article.
Review.
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Human METTL7B is an alkyl thiol methyltransferase that metabolizes hydrogen sulfide and captopril.
Maldonato BJ, Russell DA, Totah RA.
Maldonato BJ, et al.
Sci Rep. 2021 Mar 1;11(1):4857. doi: 10.1038/s41598-021-84218-5.
Sci Rep. 2021.
PMID: 33649426
Free PMC article.
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