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Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients.
Koch B, Shehata M, Müller-Ruttloff C, Gouda SA, Wetzstein N, Patyna S, Scholz A, Schmid T, Dietrich U, Münch C, Ziebuhr J, Geiger H, Martinez-Sobrido L, Baer PC, Mostafa A, Pleschka S. Koch B, et al. Among authors: muller ruttloff c. Front Cell Infect Microbiol. 2024 Mar 25;14:1363407. doi: 10.3389/fcimb.2024.1363407. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38590437 Free PMC article.
Identification of Dual Inhibitors Targeting Main Protease (Mpro) and Cathepsin L as Potential Anti-SARS-CoV-2 Agents.
Previti S, Ettari R, Calcaterra E, Roggia M, Natale B, Weldert AC, Müller-Ruttloff C, Salisch F, Irto A, Cigala RM, Ziebuhr J, Schirmeister T, Cosconati S, Zappalà M. Previti S, et al. Among authors: muller ruttloff c. ACS Med Chem Lett. 2024 Mar 1;15(5):602-609. doi: 10.1021/acsmedchemlett.3c00562. eCollection 2024 May 9. ACS Med Chem Lett. 2024. PMID: 38746883
Distinct negative-sense RNA viruses induce a common set of transcripts encoding proteins forming an extensive network.
Hofmann N, Bartkuhn M, Becker S, Biedenkopf N, Böttcher-Friebertshäuser E, Brinkrolf K, Dietzel E, Fehling SK, Goesmann A, Heindl MR, Hoffmann S, Karl N, Maisner A, Mostafa A, Kornecki L, Müller-Kräuter H, Müller-Ruttloff C, Nist A, Pleschka S, Sauerhering L, Stiewe T, Strecker T, Wilhelm J, Wuerth JD, Ziebuhr J, Weber F, Schmitz ML. Hofmann N, et al. Among authors: muller ruttloff c. J Virol. 2024 Oct 22;98(10):e0093524. doi: 10.1128/jvi.00935-24. Epub 2024 Sep 16. J Virol. 2024. PMID: 39283124 Free PMC article.
Potent anti-coronaviral activity of pateamines and new insights into their mode of action.
Magari F, Messner H, Salisch F, Schmelzle SM, van Zandbergen G, Fürstner A, Ziebuhr J, Heine A, Müller-Ruttloff C, Grünweller A. Magari F, et al. Among authors: muller ruttloff c. Heliyon. 2024 Jun 22;10(13):e33409. doi: 10.1016/j.heliyon.2024.e33409. eCollection 2024 Jul 15. Heliyon. 2024. PMID: 39035482 Free PMC article.