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Evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of SM17 in healthy volunteers: results from pre-clinical models and a first-in-human, randomized, double blinded clinical trial.
Xu G, Paglialunga S, Qian X, Ding R, Webster K, van Haarst A, Engel C, Hui CW, Lam LH, Li W, Wu WC, Rasmussen S, Hunt A, Leung SO. Xu G, et al. Among authors: hui cw. Front Immunol. 2024 Dec 9;15:1495540. doi: 10.3389/fimmu.2024.1495540. eCollection 2024. Front Immunol. 2024. PMID: 39717777 Free PMC article. Clinical Trial.
Behavioral as well as hippocampal transcriptomic and microglial responses differ across sexes in adult mouse offspring exposed to a dual genetic and environmental challenge.
Carrier M, Hui CW, Watters V, Šimončičová E, Picard K, González Ibáñez F, Vernoux N, Droit A, Desjardins M, Tremblay MÈ. Carrier M, et al. Among authors: hui cw. Brain Behav Immun. 2024 Feb;116:126-139. doi: 10.1016/j.bbi.2023.11.025. Epub 2023 Nov 26. Brain Behav Immun. 2024. PMID: 38016491
Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice.
Picard K, Bisht K, Poggini S, Garofalo S, Golia MT, Basilico B, Abdallah F, Ciano Albanese N, Amrein I, Vernoux N, Sharma K, Hui CW, C Savage J, Limatola C, Ragozzino D, Maggi L, Branchi I, Tremblay MÈ. Picard K, et al. Among authors: hui cw. Brain Behav Immun. 2021 Oct;97:423-439. doi: 10.1016/j.bbi.2021.07.022. Epub 2021 Jul 31. Brain Behav Immun. 2021. PMID: 34343616 Free article.
53 results