Kopetz SE - Search Results

1

Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer.

Yaeger R, Uboha NV, Pelster MS, Bekaii-Saab TS, Barve M, Saltzman J, Sabari JK, Peguero JA, Paulson AS, Jänne PA, Cruz-Correa M, Anderes K, Velastegui K, Yan X, Der-Torossian H, Klempner SJ, Kopetz SE. Yaeger R, et al. Among authors: kopetz se. Cancer Discov. 2024 Jun 3;14(6):982-993. doi: 10.1158/2159-8290.CD-24-0217. Cancer Discov. 2024. PMID: 38587856 Free PMC article. Clinical Trial.

2

Impact of co-mutations and transcriptional signatures in non-small cell lung cancer patients treated with adagrasib in the KRYSTAL-1 trial.

Negrao MV, Paula AG, Molkentine D, Hover L, Nilsson M, Vokes N, Engstrom L, Calinisan A, Briere DM, Waters L, Hallin J, Diao L, Altan M, Blumenschein GR, Skoulidis F, Wang J, Kopetz SE, Hong DS, Gibbons DL, Olson P, Christensen JG, Heymach JV. Negrao MV, et al. Among authors: kopetz se. Clin Cancer Res. 2025 Jan 13. doi: 10.1158/1078-0432.CCR-24-2310. Online ahead of print. Clin Cancer Res. 2025. PMID: 39804166

3

From multidisciplinary to personalized treatment of colorectal liver metastases: 4 reasons to consider RAS.

Vauthey JN, Kopetz SE. Vauthey JN, et al. Among authors: kopetz se. Cancer. 2013 Dec 1;119(23):4083-5. doi: 10.1002/cncr.28348. Epub 2013 Sep 19. Cancer. 2013. PMID: 24105015 Free article. No abstract available.

4

Meta-analysis of KRAS mutations and survival after resection of colorectal liver metastases.

Brudvik KW, Kopetz SE, Li L, Conrad C, Aloia TA, Vauthey JN. Brudvik KW, et al. Among authors: kopetz se. Br J Surg. 2015 Sep;102(10):1175-83. doi: 10.1002/bjs.9870. Epub 2015 Jul 21. Br J Surg. 2015. PMID: 26206254 Review.

5

Predictors of Safety and Efficacy of 2-Stage Hepatectomy for Bilateral Colorectal Liver Metastases.

Passot G, Chun YS, Kopetz SE, Zorzi D, Brudvik KW, Kim BJ, Conrad C, Aloia TA, Vauthey JN. Passot G, et al. Among authors: kopetz se. J Am Coll Surg. 2016 Jul;223(1):99-108. doi: 10.1016/j.jamcollsurg.2015.12.057. Epub 2016 Jan 18. J Am Coll Surg. 2016. PMID: 26968325 Free PMC article.

6

Embryonic origin of primary colon cancer predicts survival in patients undergoing ablation for colorectal liver metastases.

Yamashita S, Odisio BC, Huang SY, Kopetz SE, Ahrar K, Chun YS, Conrad C, Aloia TA, Gupta S, Harmoush S, Hicks ME, Vauthey JN. Yamashita S, et al. Among authors: kopetz se. Eur J Surg Oncol. 2017 Jun;43(6):1040-1049. doi: 10.1016/j.ejso.2017.01.007. Epub 2017 Jan 29. Eur J Surg Oncol. 2017. PMID: 28187878

7

Deleterious Effect of RAS and Evolutionary High-risk TP53 Double Mutation in Colorectal Liver Metastases.

Chun YS, Passot G, Yamashita S, Nusrat M, Katsonis P, Loree JM, Conrad C, Tzeng CD, Xiao L, Aloia TA, Eng C, Kopetz SE, Lichtarge O, Vauthey JN. Chun YS, et al. Among authors: kopetz se. Ann Surg. 2019 May;269(5):917-923. doi: 10.1097/SLA.0000000000002450. Ann Surg. 2019. PMID: 28767562 Free PMC article.

8

BCL-X_L PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRAS^G12C-mutated cancers.

Khan S, Wiegand J, Zhang P, Hu W, Thummuri D, Budamagunta V, Hua N, Jin L, Allegra CJ, Kopetz SE, Zajac-Kaye M, Kaye FJ, Zheng G, Zhou D. Khan S, et al. Among authors: kopetz se. J Hematol Oncol. 2022 Mar 9;15(1):23. doi: 10.1186/s13045-022-01241-3. J Hematol Oncol. 2022. PMID: 35260176 Free PMC article.

9

Combined KRAS^G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS^G12C-driven cancers by addressing intrinsic and acquired resistance.

Thatikonda V, Lu H, Jurado S, Kostyrko K, Bristow CA, Bosch K, Feng N, Gao S, Gerlach D, Gmachl M, Lieb S, Jeschko A, Machado AA, Marszalek ED, Mahendra M, Jaeger PA, Sorokin A, Strauss S, Trapani F, Kopetz S, Vellano CP, Petronczki M, Kraut N, Heffernan TP, Marszalek JR, Pearson M, Waizenegger I, Hofmann MH. Thatikonda V, et al. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525210. doi: 10.1101/2023.01.23.525210. bioRxiv. 2023. Update in: Nat Cancer. 2024 Sep;5(9):1352-1370. doi: 10.1038/s43018-024-00800-6 PMID: 36747713 Free PMC article. Updated. Preprint.

10

RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases.

Vauthey JN, Zimmitti G, Kopetz SE, Shindoh J, Chen SS, Andreou A, Curley SA, Aloia TA, Maru DM. Vauthey JN, et al. Among authors: kopetz se. Ann Surg. 2013 Oct;258(4):619-26; discussion 626-7. doi: 10.1097/SLA.0b013e3182a5025a. Ann Surg. 2013. PMID: 24018645 Free PMC article.

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