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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.
Picco G, Rao Y, Al Saedi A, Lee Y, Vieira SF, Bhosle S, May K, Herranz-Ors C, Walker SJ, Shenje R, Dincer C, Gibson F, Banerjee R, Hewitson Z, Werner T, Cottom JE, Peng Y, Deng N, Zhang Y, Nartey EN, Nickels L, Landis P, Conticelli D, McCarten K, Bush J, Sharma M, Lightfoot H, House D, Milford E, Grant EK, Glogowski MP, Wagner CD, Bantscheff M, Rutkowska-Klute A; Cell Model Network UK Group; Zappacosta F, Pettinger J, Barthorpe S, Eberl HC, Jones BT, Schneck JL, Murphy DJ, Voest EE, Taygerly JP, DeMartino MP, Coelho MA, Houseley J, Sharma G, Schwartz B, Garnett MJ. Picco G, et al. Among authors: mccarten k. Cancer Discov. 2024 Aug 2;14(8):1457-1475. doi: 10.1158/2159-8290.CD-24-0052. Cancer Discov. 2024. PMID: 38587317 Free PMC article.
Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.
Bashi AC, Coker EA, Bulusu KC, Jaaks P, Crafter C, Lightfoot H, Milo M, McCarten K, Jenkins DF, van der Meer D, Lynch JT, Barthorpe S, Andersen CL, Barry ST, Beck A, Cidado J, Gordon JA, Hall C, Hall J, Mali I, Mironenko T, Mongeon K, Morris J, Richardson L, Smith PD, Tavana O, Tolley C, Thomas F, Willis BS, Yang W, O'Connor MJ, McDermott U, Critchlow SE, Drew L, Fawell SE, Mettetal JT, Garnett MJ. Bashi AC, et al. Among authors: mccarten k. Cancer Discov. 2024 May 1;14(5):846-865. doi: 10.1158/2159-8290.CD-23-0388. Cancer Discov. 2024. PMID: 38456804 Free PMC article.
Base editing screens define the genetic landscape of cancer drug resistance mechanisms.
Coelho MA, Strauss ME, Watterson A, Cooper S, Bhosle S, Illuzzi G, Karakoc E, Dinçer C, Vieira SF, Sharma M, Moullet M, Conticelli D, Koeppel J, McCarten K, Cattaneo CM, Veninga V, Picco G, Parts L, Forment JV, Voest EE, Marioni JC, Bassett A, Garnett MJ. Coelho MA, et al. Among authors: mccarten k. Nat Genet. 2024 Nov;56(11):2479-2492. doi: 10.1038/s41588-024-01948-8. Epub 2024 Oct 18. Nat Genet. 2024. PMID: 39424923 Free PMC article.
Modelling quiescence exit of neural stem cells reveals a FOXG1-FOXO6 axis.
Ferguson KM, Blin C, Garcia-Diaz C, Bulstrode H, Bardini Bressan R, McCarten K, Pollard SM. Ferguson KM, et al. Among authors: mccarten k. Dis Model Mech. 2024 Dec 1;17(12):dmm052005. doi: 10.1242/dmm.052005. Epub 2024 Nov 29. Dis Model Mech. 2024. PMID: 39499086 Free PMC article.
Pulmonary lesions in early response assessment in pediatric Hodgkin lymphoma: prevalence and possible implications for initial staging.
Stoevesandt D, Ludwig C, Mauz-Körholz C, Körholz D, Hasenclever D, McCarten K, Flerlage JE, Kurch L, Wohlgemuth WA, Landman-Parker J, Wallace WH, Fosså A, Vordermark D, Karlén J, Cepelová M, Klekawka T, Attarbaschi A, Hraskova A, Uyttebroeck A, Beishuizen A, Dieckmann K, Leblanc T, Daw S, Steglich J. Stoevesandt D, et al. Among authors: mccarten k. Pediatr Radiol. 2024 May;54(5):725-736. doi: 10.1007/s00247-024-05859-y. Epub 2024 Jan 31. Pediatr Radiol. 2024. PMID: 38296856 Free PMC article.
Prognostic value of chest x-ray- and CT-defined large mediastinal adenopathy in high-risk pediatric Hodgkin lymphoma: A report from the Children's Oncology Group Study AHOD0831.
Lo AC, Lee I, Pei Q, Wu Y, McCarten KM, Hoppe BS, Hodgson DC, Roberts K, Milgrom S, Kessel S, Cole PD, Kelly KM, Cho SY. Lo AC, et al. Among authors: mccarten km. Pediatr Blood Cancer. 2023 Aug;70(8):e30452. doi: 10.1002/pbc.30452. Epub 2023 May 27. Pediatr Blood Cancer. 2023. PMID: 37243975 Free PMC article.
70 results