Yan J - Search Results

1

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial.

Yarchoan M, Gane EJ, Marron TU, Perales-Linares R, Yan J, Cooch N, Shu DH, Fertig EJ, Kagohara LT, Bartha G, Northcott J, Lyle J, Rochestie S, Peters J, Connor JT, Jaffee EM, Csiki I, Weiner DB, Perales-Puchalt A, Sardesai NY. Yarchoan M, et al. Among authors: yan j. Nat Med. 2024 Apr;30(4):1044-1053. doi: 10.1038/s41591-024-02894-y. Epub 2024 Apr 7. Nat Med. 2024. PMID: 38584166 Free PMC article. Clinical Trial.

2

Hepatitis C virus NS3/NS4A DNA vaccine induces multiepitope T cell responses in rhesus macaques mimicking human immune responses [corrected].

Lang Kuhs KA, Ginsberg AA, Yan J, Wiseman RW, Khan AS, Sardesai NY, O'Connor DH, Weiner DB. Lang Kuhs KA, et al. Among authors: yan j. Mol Ther. 2012 Mar;20(3):669-78. doi: 10.1038/mt.2011.188. Epub 2011 Sep 27. Mol Ther. 2012. PMID: 21952169 Free PMC article.

3

Induction of robust cellular immunity against HPV6 and HPV11 in mice by DNA vaccine encoding for E6/E7 antigen.

Shin TH, Pankhong P, Yan J, Khan AS, Sardesai NY, Weiner DB. Shin TH, et al. Among authors: yan j. Hum Vaccin Immunother. 2012 Apr;8(4):470-8. doi: 10.4161/hv.19180. Epub 2012 Feb 16. Hum Vaccin Immunother. 2012. PMID: 22336879 Free PMC article.

4

IL-28B/IFN-lambda 3 drives granzyme B loading and significantly increases CTL killing activity in macaques.

Morrow MP, Yan J, Pankhong P, Shedlock DJ, Lewis MG, Talbott K, Toporovski R, Khan AS, Sardesai NY, Weiner DB. Morrow MP, et al. Among authors: yan j. Mol Ther. 2010 Sep;18(9):1714-23. doi: 10.1038/mt.2010.118. Epub 2010 Jun 22. Mol Ther. 2010. PMID: 20571540 Free PMC article.

5

Strong HCV NS3/4a, NS4b, NS5a, NS5b-specific cellular immune responses induced in Rhesus macaques by a novel HCV genotype 1a/1b consensus DNA vaccine.

Latimer B, Toporovski R, Yan J, Pankhong P, Morrow MP, Khan AS, Sardesai NY, Welles SL, Jacobson JM, Weiner DB, Kutzler MA. Latimer B, et al. Among authors: yan j. Hum Vaccin Immunother. 2014;10(8):2357-65. doi: 10.4161/hv.29590. Hum Vaccin Immunother. 2014. PMID: 25424943 Free PMC article.

6

Alteration of the Tumor Stroma Using a Consensus DNA Vaccine Targeting Fibroblast Activation Protein (FAP) Synergizes with Antitumor Vaccine Therapy in Mice.

Duperret EK, Trautz A, Ammons D, Perales-Puchalt A, Wise MC, Yan J, Reed C, Weiner DB. Duperret EK, et al. Among authors: yan j. Clin Cancer Res. 2018 Mar 1;24(5):1190-1201. doi: 10.1158/1078-0432.CCR-17-2033. Epub 2017 Dec 21. Clin Cancer Res. 2018. PMID: 29269377 Free PMC article.

7

Designing consensus immunogens to break tolerance to self-antigens for cancer therapy.

Duperret EK, Yan J, Weiner DB. Duperret EK, et al. Among authors: yan j. Oncotarget. 2018 Oct 30;9(85):35513-35514. doi: 10.18632/oncotarget.26275. eCollection 2018 Oct 30. Oncotarget. 2018. PMID: 30473745 Free PMC article. No abstract available.

8

A Novel DNA Vaccine Platform Enhances Neo-antigen-like T Cell Responses against WT1 to Break Tolerance and Induce Anti-tumor Immunity.

Walters JN, Ferraro B, Duperret EK, Kraynyak KA, Chu J, Saint-Fleur A, Yan J, Levitsky H, Khan AS, Sardesai NY, Weiner DB. Walters JN, et al. Among authors: yan j. Mol Ther. 2017 Apr 5;25(4):976-988. doi: 10.1016/j.ymthe.2017.01.022. Epub 2017 Feb 22. Mol Ther. 2017. PMID: 28237837 Free PMC article.

9

Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity.

Yan J, Pankhong P, Shin TH, Obeng-Adjei N, Morrow MP, Walters JN, Khan AS, Sardesai NY, Weiner DB. Yan J, et al. Cancer Immunol Res. 2013 Sep;1(3):179-189. doi: 10.1158/2326-6066.CIR-13-0001. Epub 2013 Jul 17. Cancer Immunol Res. 2013. PMID: 24777680 Free PMC article.

10

Engineered DNA Vaccination against Follicle-Stimulating Hormone Receptor Delays Ovarian Cancer Progression in Animal Models.

Perales-Puchalt A, Wojtak K, Duperret EK, Yang X, Slager AM, Yan J, Muthumani K, Montaner LJ, Weiner DB. Perales-Puchalt A, et al. Among authors: yan j. Mol Ther. 2019 Feb 6;27(2):314-325. doi: 10.1016/j.ymthe.2018.11.014. Epub 2018 Dec 13. Mol Ther. 2019. PMID: 30554854 Free PMC article.

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