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Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection.
Wu H, Wang J, Cheng H, Gao Y, Liu W, Zhang Z, Jiang H, Li W, Zhu F, Lv M, Liu C, Tan Q, Zhang X, Wang C, Ni X, Chen Y, Song B, Zhou P, Wei Z, Zhang F, He X, Cao Y. Wu H, et al. Among authors: cheng h. J Assist Reprod Genet. 2020 Apr;37(4):829-840. doi: 10.1007/s10815-020-01721-w. Epub 2020 Mar 2. J Assist Reprod Genet. 2020. PMID: 32124190 Free PMC article.
A novel hemizygous loss-of-function mutation in ADGRG2 causes male infertility with congenital bilateral absence of the vas deferens.
Wu H, Gao Y, Ma C, Shen Q, Wang J, Lv M, Liu C, Cheng H, Zhu F, Tian S, Elshewy N, Ni X, Tan Q, Xu X, Zhou P, Wei Z, Zhang F, He X, Cao Y. Wu H, et al. Among authors: cheng h. J Assist Reprod Genet. 2020 Jun;37(6):1421-1429. doi: 10.1007/s10815-020-01779-6. Epub 2020 Apr 20. J Assist Reprod Genet. 2020. PMID: 32314195 Free PMC article.
A novel homozygous mutation in WDR19 induces disorganization of microtubules in sperm flagella and nonsyndromic asthenoteratospermia.
Ni X, Wang J, Lv M, Liu C, Zhong Y, Tian S, Wu H, Cheng H, Gao Y, Tan Q, Chen B, Li Q, Song B, Wei Z, Zhou P, He X, Zhang F, Cao Y. Ni X, et al. Among authors: cheng h. J Assist Reprod Genet. 2020 Jun;37(6):1431-1439. doi: 10.1007/s10815-020-01770-1. Epub 2020 Apr 23. J Assist Reprod Genet. 2020. PMID: 32323121 Free PMC article.
Novel bi-allelic variants in DNAH2 cause severe asthenoteratozoospermia with multiple morphological abnormalities of the flagella.
Gao Y, Tian S, Sha Y, Zha X, Cheng H, Wang A, Liu C, Lv M, Ni X, Li Q, Wu H, Tan Q, Tang D, Song B, Ding D, Cong J, Xu Y, Zhou P, Wei Z, Cao Y, Xu Y, Zhang F, He X. Gao Y, et al. Among authors: cheng h. Reprod Biomed Online. 2021 May;42(5):963-972. doi: 10.1016/j.rbmo.2021.01.011. Epub 2021 Jan 22. Reprod Biomed Online. 2021. PMID: 33771466
Novel deleterious splicing variant in HFM1 causes gametogenesis defect and recurrent implantation failure: concerning the risk of chromosomal abnormalities in embryos.
Tang F, Gao Y, Li K, Tang D, Hao Y, Lv M, Wu H, Cheng H, Fei J, Jin Z, Wang C, Xu Y, Wei Z, Zhou P, Zhang Z, He X, Cao Y. Tang F, et al. Among authors: cheng h. J Assist Reprod Genet. 2023 Jul;40(7):1689-1702. doi: 10.1007/s10815-023-02761-8. Epub 2023 Mar 3. J Assist Reprod Genet. 2023. PMID: 36864181 Free PMC article.
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