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The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.
Robey RW, Fitzsimmons CM, Guiblet WM, Frye WJE, González Dalmasy JM, Wang L, Russell DA, Huff LM, Perciaccante AJ, Ali-Rahmani F, Lipsey CC, Wade HM, Mitchell AV, Maligireddy SS, Terrero D, Butcher D, Edmondson EF, Jenkins LM, Nikitina T, Zhurkin VB, Tiwari AK, Piscopio AD, Totah RA, Bates SE, Arda HE, Gottesman MM, Batista PJ. Robey RW, et al. Among authors: gonzalez dalmasy jm. Mol Cancer Ther. 2024 Apr 2;23(4):464-477. doi: 10.1158/1535-7163.MCT-23-0144. Mol Cancer Ther. 2024. PMID: 38151817 Free PMC article.
The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species.
González Dalmasy JM, Fitzsimmons CM, Frye WJE, Perciaccante AJ, Jewell CP, Jenkins LM, Batista PJ, Robey RW, Gottesman MM. González Dalmasy JM, et al. bioRxiv [Preprint]. 2023 Nov 17:2023.11.17.567538. doi: 10.1101/2023.11.17.567538. bioRxiv. 2023. Update in: Chem Biol Interact. 2024 May 1;394:110989. doi: 10.1016/j.cbi.2024.110989 PMID: 38076968 Free PMC article. Updated. Preprint.