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Page 1
The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species.
González Dalmasy JM, Fitzsimmons CM, Frye WJE, Perciaccante AJ, Jewell CP, Jenkins LM, Batista PJ, Robey RW, Gottesman MM. González Dalmasy JM, et al. Among authors: frye wje. Chem Biol Interact. 2024 May 1;394:110989. doi: 10.1016/j.cbi.2024.110989. Epub 2024 Apr 3. Chem Biol Interact. 2024. PMID: 38574836
The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models.
Hebron KE, Wan X, Roth JS, Liewehr DJ, Sealover NE, Frye WJE, Kim A, Stauffer S, Perkins OL, Sun W, Isanogle KA, Robinson CM, James A, Awasthi P, Shankarappa P, Luo X, Lei H, Butcher D, Smith R, Edmondson EF, Chen JQ, Kedei N, Peer CJ, Shern JF, Figg WD, Chen L, Hall MD, Difilippantonio S, Barr FG, Kortum RL, Robey RW, Vaseva AV, Khan J, Yohe ME. Hebron KE, et al. Among authors: frye wje. Clin Cancer Res. 2023 Jan 17;29(2):472-487. doi: 10.1158/1078-0432.CCR-22-1646. Clin Cancer Res. 2023. PMID: 36322002 Free PMC article.
The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers.
Frye WJE, Huff LM, Dalmasy JMG, Salazar P, Carter RM, Gensler RT, Esposito D, Robey RW, Ambudkar SV, Gottesman MM. Frye WJE, et al. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529736. doi: 10.1101/2023.02.23.529736. bioRxiv. 2023. Update in: Cancer Drug Resist. 2023 Jul 27;6(6):468-480. doi: 10.20517/cdr.2023.29 PMID: 36945397 Free PMC article. Updated. Preprint.
Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier.
Thomas JR, Frye WJE, Robey RW, Warner AC, Butcher D, Matta JL, Morgan TC, Edmondson EF, Salazar PB, Ambudkar SV, Gottesman MM. Thomas JR, et al. Among authors: frye wje. bioRxiv [Preprint]. 2024 Jan 8:2023.05.18.539313. doi: 10.1101/2023.05.18.539313. bioRxiv. 2024. Update in: Fluids Barriers CNS. 2024 Mar 15;21(1):27. doi: 10.1186/s12987-024-00529-5 PMID: 37425689 Free PMC article. Updated. Preprint.
The thiol methyltransferase activity of TMT1A (METTL7A) is conserved across species.
González Dalmasy JM, Fitzsimmons CM, Frye WJE, Perciaccante AJ, Jewell CP, Jenkins LM, Batista PJ, Robey RW, Gottesman MM. González Dalmasy JM, et al. Among authors: frye wje. bioRxiv [Preprint]. 2023 Nov 17:2023.11.17.567538. doi: 10.1101/2023.11.17.567538. bioRxiv. 2023. Update in: Chem Biol Interact. 2024 May 1;394:110989. doi: 10.1016/j.cbi.2024.110989 PMID: 38076968 Free PMC article. Updated. Preprint.
The Methyltransferases METTL7A and METTL7B Confer Resistance to Thiol-Based Histone Deacetylase Inhibitors.
Robey RW, Fitzsimmons CM, Guiblet WM, Frye WJE, González Dalmasy JM, Wang L, Russell DA, Huff LM, Perciaccante AJ, Ali-Rahmani F, Lipsey CC, Wade HM, Mitchell AV, Maligireddy SS, Terrero D, Butcher D, Edmondson EF, Jenkins LM, Nikitina T, Zhurkin VB, Tiwari AK, Piscopio AD, Totah RA, Bates SE, Arda HE, Gottesman MM, Batista PJ. Robey RW, et al. Among authors: frye wje. Mol Cancer Ther. 2024 Apr 2;23(4):464-477. doi: 10.1158/1535-7163.MCT-23-0144. Mol Cancer Ther. 2024. PMID: 38151817 Free PMC article.
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.
Lim S, Kwak M, Kang J, Cesaire M, Tang K, Robey RW, Frye WJE, Karim B, Butcher D, Lizak MJ, Dalmage M, Foster B, Nuechterlein N, Eberhart C, Cimino PJ, Gottesman MM, Jackson S. Lim S, et al. Among authors: frye wje. Acta Neuropathol Commun. 2024 Apr 8;12(1):56. doi: 10.1186/s40478-024-01763-6. Acta Neuropathol Commun. 2024. PMID: 38589905 Free PMC article.