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Discovery of novel quinolin-2-one derivatives as potential GSK-3β inhibitors for treatment of Alzheimer's disease: Pharmacophore-based design, preliminary SAR, in vitro and in vivo biological evaluation.
Abdo Moustafa E, Abdelrasheed Allam H, Fouad MA, El Kerdawy AM, Nasser Eid El-Sayed N, Wagner C, Abdel-Aziz HA, Abdel Fattah Ezzat M. Abdo Moustafa E, et al. Among authors: abdelrasheed allam h. Bioorg Chem. 2024 May;146:107324. doi: 10.1016/j.bioorg.2024.107324. Epub 2024 Mar 30. Bioorg Chem. 2024. PMID: 38569322
Arylidine extensions of 3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-benzenesulfonamide derivatives: Synthesis, computational simulations and biological evaluation as tumor-associated carbonic anhydrase inhibitors.
Metwally HM, Abdelrasheed Allam H, Baselious F, Bonardi A, Seif EM, Moussa SA, Abdel-Latif E, Supuran CT, Ibrahim HS. Metwally HM, et al. Among authors: abdelrasheed allam h. Bioorg Chem. 2023 Jun;135:106492. doi: 10.1016/j.bioorg.2023.106492. Epub 2023 Mar 24. Bioorg Chem. 2023. PMID: 37001471