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Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.
Zeitlin L, Cross RW, Woolsey C, West BR, Borisevich V, Agans KN, Prasad AN, Deer DJ, Stuart L, McCavitt-Malvido M, Kim DH, Pettitt J, Crowe JE Jr, Whaley KJ, Veesler D, Dimitrov A, Abelson DM, Geisbert TW, Broder CC. Zeitlin L, et al. Among authors: broder cc. Sci Transl Med. 2024 Apr 3;16(741):eadl2055. doi: 10.1126/scitranslmed.adl2055. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569014
Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus.
Bonaparte MI, Dimitrov AS, Bossart KN, Crameri G, Mungall BA, Bishop KA, Choudhry V, Dimitrov DS, Wang LF, Eaton BT, Broder CC. Bonaparte MI, et al. Among authors: broder cc. Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10652-7. doi: 10.1073/pnas.0504887102. Epub 2005 Jul 5. Proc Natl Acad Sci U S A. 2005. PMID: 15998730 Free PMC article.
Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies.
Zhu Z, Dimitrov AS, Bossart KN, Crameri G, Bishop KA, Choudhry V, Mungall BA, Feng YR, Choudhary A, Zhang MY, Feng Y, Wang LF, Xiao X, Eaton BT, Broder CC, Dimitrov DS. Zhu Z, et al. Among authors: broder cc. J Virol. 2006 Jan;80(2):891-9. doi: 10.1128/JVI.80.2.891-899.2006. J Virol. 2006. PMID: 16378991 Free PMC article.
221 results