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Page 1
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis.
Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss NJ, O'Sullivan J, Brierley CK, Clark SA, Pérez Sáez JM, Fernández PA, Schoof EM, Porse B, Meng Y, Khan AO, Wen S, Dong P, Zhou W, Sousos N, Murphy L, Clarke M, Olijnik AA, Wong ZC, Karali CS, Sirinukunwattana K, Ryou H, Norfo R, Cheng Q, Carrelha J, Ren Z, Thongjuea S, Rathinam VA, Krishnan A, Royston D, Rabinovich GA, Mead AJ, Psaila B. Li R, et al. Among authors: jooss nj. Sci Transl Med. 2024 Oct 9;16(768):eadj7552. doi: 10.1126/scitranslmed.adj7552. Epub 2024 Oct 9. Sci Transl Med. 2024. PMID: 39383242 Free PMC article.
Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.
Smith CW, Campos J, Brown HC, Jooss NJ, Ivanova VS, Harbi M, Garcia-Quintanilla L, Jossi S, Perez-Toledo M, Rookes K, Brill A, Theodore LN, Owens T, LaStant J, Foulke MC, Mukai S, Francesco M, Storek M, Hicks A, Langrish C, Nunn PA, Cunningham AF, Chauhan A, Thomas MR, Watson SP, Nicolson PLR. Smith CW, et al. Among authors: jooss nj. Blood Adv. 2024 Nov 12;8(21):5557-5570. doi: 10.1182/bloodadvances.2024012713. Blood Adv. 2024. PMID: 38968150 Free PMC article.
Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.
Damaskinaki FN, Jooss NJ, Martin EM, Clark JC, Thomas MR, Poulter NS, Emsley J, Kellam B, Watson SP, Slater A. Damaskinaki FN, et al. Among authors: jooss nj. J Thromb Haemost. 2023 Feb;21(2):317-328. doi: 10.1016/j.jtha.2022.11.002. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36700508 Free article.
17 results