Wu Y - Search Results

1

Purification and biochemical characterization of the G4 resolvase and DNA helicase FANCJ.

Kulikowicz T, Sommers JA, Fuchs KF, Wu Y, Brosh RM Jr. Kulikowicz T, et al. Among authors: wu y. Methods Enzymol. 2024;695:1-27. doi: 10.1016/bs.mie.2023.12.006. Epub 2024 Jan 5. Methods Enzymol. 2024. PMID: 38521581

2

FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability.

Wu Y, Shin-ya K, Brosh RM Jr. Wu Y, et al. Mol Cell Biol. 2008 Jun;28(12):4116-28. doi: 10.1128/MCB.02210-07. Epub 2008 Apr 21. Mol Cell Biol. 2008. PMID: 18426915 Free PMC article.

3

Welcome the family of FANCJ-like helicases to the block of genome stability maintenance proteins.

Wu Y, Suhasini AN, Brosh RM Jr. Wu Y, et al. Cell Mol Life Sci. 2009 Apr;66(7):1209-22. doi: 10.1007/s00018-008-8580-6. Cell Mol Life Sci. 2009. PMID: 19099189 Free PMC article. Review.

4

FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress.

Wu Y, Brosh RM Jr. Wu Y, et al. Curr Mol Med. 2009 May;9(4):470-82. doi: 10.2174/156652409788167159. Curr Mol Med. 2009. PMID: 19519404 Free PMC article. Review.

5

Molecular analyses of DNA helicases involved in the replicational stress response.

Wu Y, Sommers JA, Suhasini AN, Aggarwal M, Brosh RM. Wu Y, et al. Methods. 2010 Jul;51(3):303-12. doi: 10.1016/j.ymeth.2010.02.021. Epub 2010 Feb 25. Methods. 2010. PMID: 20188837 Free PMC article. Review.

6

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.

Wu Y, Sommers JA, Suhasini AN, Leonard T, Deakyne JS, Mazin AV, Shin-Ya K, Kitao H, Brosh RM Jr. Wu Y, et al. Blood. 2010 Nov 11;116(19):3780-91. doi: 10.1182/blood-2009-11-256016. Epub 2010 Jul 16. Blood. 2010. PMID: 20639400 Free PMC article.

7

G-quadruplex nucleic acids and human disease.

Wu Y, Brosh RM Jr. Wu Y, et al. FEBS J. 2010 Sep;277(17):3470-88. doi: 10.1111/j.1742-4658.2010.07760.x. Epub 2010 Jul 29. FEBS J. 2010. PMID: 20670277 Free PMC article. Review.

8

Helicase-inactivating mutations as a basis for dominant negative phenotypes.

Wu Y, Brosh RM Jr. Wu Y, et al. Cell Cycle. 2010 Oct 15;9(20):4080-90. doi: 10.4161/cc.9.20.13667. Cell Cycle. 2010. PMID: 20980836 Free PMC article. Review.

9

Biochemical characterization of Warsaw breakage syndrome helicase.

Wu Y, Sommers JA, Khan I, de Winter JP, Brosh RM Jr. Wu Y, et al. J Biol Chem. 2012 Jan 6;287(2):1007-21. doi: 10.1074/jbc.M111.276022. Epub 2011 Nov 18. J Biol Chem. 2012. PMID: 22102414 Free PMC article.

10

The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function.

Wu Y, Sommers JA, Loiland JA, Kitao H, Kuper J, Kisker C, Brosh RM Jr. Wu Y, et al. J Biol Chem. 2012 Jun 22;287(26):21699-716. doi: 10.1074/jbc.M112.351338. Epub 2012 May 10. J Biol Chem. 2012. PMID: 22582397 Free PMC article.

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