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Page 1
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa.
Rajcsanyi LS, Hoffmann A, Ghosh A, Matrisch-Dinkler B, Zheng Y, Peters T, Sun W, Dong H, Noé F, Wolfrum C, Herpertz-Dahlmann B, Seitz J, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Giel K, Egberts K, Burghardt R, Föcker M, Tsai LT, Müller TD, Blüher M, Hebebrand J, Hirtz R, Hinney A. Rajcsanyi LS, et al. Among authors: bluher m. Front Genet. 2023 Apr 10;14:1128133. doi: 10.3389/fgene.2023.1128133. eCollection 2023. Front Genet. 2023. PMID: 37101650 Free PMC article.
Unveiling adipose populations linked to metabolic health in obesity.
Reinisch I, Ghosh A, Noé F, Sun W, Dong H, Leary P, Dietrich A, Hoffmann A, Blüher M, Wolfrum C. Reinisch I, et al. Among authors: bluher m. Cell Metab. 2024 Dec 11:S1550-4131(24)00452-2. doi: 10.1016/j.cmet.2024.11.006. Online ahead of print. Cell Metab. 2024. PMID: 39694039 Free article.
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, Rayner NW, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B, Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, … See abstract for full author list ➔ Gaulton KJ, et al. Among authors: bluher m. Nat Genet. 2015 Dec;47(12):1415-25. doi: 10.1038/ng.3437. Epub 2015 Nov 9. Nat Genet. 2015. PMID: 26551672 Free PMC article.
Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions.
Schönauer R, Jin W, Findeisen C, Valenzuela I, Devlin LA, Murrell J, Bedoukian EC, Pöschla L, Hantmann E, Riedhammer KM, Hoefele J, Platzer K, Biemann R, Campeau PM, Münch J, Heyne H, Hoffmann A, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Woods E, Parker MJ, Neatu R, Le Guyader G, Bruel AL, Perrin L, Spiewak H; Genomics England Research Consortium; Missotte I, Fourgeaud M, Michaud V, Lacombe D, Paolucci SA, Buchan JG, Glissmeyer M, Popp B, Blüher M, Sayer JA, Halbritter J. Schönauer R, et al. Among authors: bluher m. Am J Hum Genet. 2023 Jun 1;110(6):998-1007. doi: 10.1016/j.ajhg.2023.04.010. Epub 2023 May 18. Am J Hum Genet. 2023. PMID: 37207645 Free PMC article.
Long-term green-Mediterranean diet may favor fasting morning cortisol stress hormone; the DIRECT-PLUS clinical trial.
Alufer L, Tsaban G, Rinott E, Kaplan A, Meir AY, Zelicha H, Ceglarek U, Isermann B, Blüher M, Stumvoll M, Stampfer MJ, Shai I. Alufer L, et al. Among authors: bluher m. Front Endocrinol (Lausanne). 2023 Nov 14;14:1243910. doi: 10.3389/fendo.2023.1243910. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38034010 Free PMC article. Clinical Trial.
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, Glawitsch L, Heitzer E, Schulz TJ, Schupp M, Sun W, Dong H, Ghosh A, Hoffmann A, Kratky D, Hinte LC, von Meyenn F, Heck AJR, Blüher M, Herzig S, Wolfrum C, Prokesch A. Reinisch I, et al. Among authors: bluher m. Nat Commun. 2024 Feb 15;15(1):1391. doi: 10.1038/s41467-024-45724-y. Nat Commun. 2024. PMID: 38360943 Free PMC article.
Fas (CD95) expression in adipocytes contributes to diet-induced obesity.
Wueest S, Scaffidi C, van Krieken PP, Konrad NK, Koch C, Wiedemann MSF, Goergen A, Borsigova M, Lempesis IG, Fullin J, Manolopoulos KN, Böttcher S, Goossens GH, Blüher M, Konrad D. Wueest S, et al. Among authors: bluher m. Obesity (Silver Spring). 2024 Oct;32(10):1812-1818. doi: 10.1002/oby.24092. Epub 2024 Jul 17. Obesity (Silver Spring). 2024. PMID: 39020501
771 results