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Page 1
A heterogeneous pharmaco-transcriptomic landscape induced by targeting a single oncogenic kinase.
Giglio RM, Hou N, Wyatt A, Hong J, Shi L, Vaikunthan M, Fuchs H, Nima JP, Malinowski SW, Ligon KL, McFaline-Figueroa JR, Yosef N, Azizi E, McFaline-Figueroa JL. Giglio RM, et al. Among authors: mcfaline figueroa jl. bioRxiv [Preprint]. 2024 Apr 10:2024.04.08.587960. doi: 10.1101/2024.04.08.587960. bioRxiv. 2024. PMID: 38645018 Free PMC article. Preprint.
Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs.
He S, Jin Y, Nazaret A, Shi L, Chen X, Rampersaud S, Dhillon BS, Valdez I, Friend LE, Fan JL, Park CY, Mintz RL, Lao YH, Carrera D, Fang KW, Mehdi K, Rohde M, McFaline-Figueroa JL, Blei D, Leong KW, Rudensky AY, Plitas G, Azizi E. He S, et al. Among authors: mcfaline figueroa jl. Nat Biotechnol. 2024 Mar 21:10.1038/s41587-024-02173-8. doi: 10.1038/s41587-024-02173-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 38514799
Mitosis exit followed by death in interphase prevents the development of polyploid giant cancer cells.
Vicente JJ, Khan K, Tillinghast G, McFaline-Figueroa JL, Sancak Y, Stella N. Vicente JJ, et al. Among authors: mcfaline figueroa jl. bioRxiv [Preprint]. 2023 Oct 5:2023.08.31.555795. doi: 10.1101/2023.08.31.555795. bioRxiv. 2023. Update in: J Transl Med. 2024 May 10;22(1):441. doi: 10.1186/s12967-024-05234-3 PMID: 37693393 Free PMC article. Updated. Preprint.
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy.
McFaline-Figueroa JL, Srivatsan S, Hill AJ, Gasperini M, Jackson DL, Saunders L, Domcke S, Regalado SG, Lazarchuck P, Alvarez S, Monnat RJ Jr, Shendure J, Trapnell C. McFaline-Figueroa JL, et al. bioRxiv [Preprint]. 2023 Jun 14:2023.03.10.531983. doi: 10.1101/2023.03.10.531983. bioRxiv. 2023. Update in: Cell Genom. 2024 Feb 14;4(2):100487. doi: 10.1016/j.xgen.2023.100487 PMID: 37398090 Free PMC article. Updated. Preprint.
Predicting cellular responses to complex perturbations in high-throughput screens.
Lotfollahi M, Klimovskaia Susmelj A, De Donno C, Hetzel L, Ji Y, Ibarra IL, Srivatsan SR, Naghipourfar M, Daza RM, Martin B, Shendure J, McFaline-Figueroa JL, Boyeau P, Wolf FA, Yakubova N, Günnemann S, Trapnell C, Lopez-Paz D, Theis FJ. Lotfollahi M, et al. Among authors: mcfaline figueroa jl. Mol Syst Biol. 2023 Jun 12;19(6):e11517. doi: 10.15252/msb.202211517. Epub 2023 May 8. Mol Syst Biol. 2023. PMID: 37154091 Free PMC article.
High-Capacity Sample Multiplexing for Single Cell Chromatin Accessibility Profiling.
Booth GT, Daza RM, Srivatsan SR, McFaline-Figueroa JL, Gladden RG, Furlan SN, Shendure J, Trapnell C. Booth GT, et al. Among authors: mcfaline figueroa jl. bioRxiv [Preprint]. 2023 Mar 6:2023.03.05.531201. doi: 10.1101/2023.03.05.531201. bioRxiv. 2023. Update in: BMC Genomics. 2023 Dec 4;24(1):737. doi: 10.1186/s12864-023-09832-1 PMID: 36945538 Free PMC article. Updated. Preprint.
26 results