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IL7 increases targeted lipid nanoparticle-mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation.
Tilsed CM, Sadiq BA, Papp TE, Areesawangkit P, Kimura K, Noguera-Ortega E, Scholler J, Cerda N, Aghajanian H, Bot A, Mui B, Tam Y, Weissman D, June CH, Albelda SM, Parhiz H. Tilsed CM, et al. Among authors: scholler j. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2319856121. doi: 10.1073/pnas.2319856121. Epub 2024 Mar 21. Proc Natl Acad Sci U S A. 2024. PMID: 38513098 Free PMC article.
Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors.
Kalbasi A, Siurala M, Su LL, Tariveranmoshabad M, Picton LK, Ravikumar P, Li P, Lin JX, Escuin-Ordinas H, Da T, Kremer SV, Sun AL, Castelli S, Agarwal S, Scholler J, Song D, Rommel PC, Radaelli E, Young RM, Leonard WJ, Ribas A, June CH, Garcia KC. Kalbasi A, et al. Among authors: scholler j. Nature. 2022 Dec;612(7938):E10. doi: 10.1038/s41586-022-05548-6. Nature. 2022. PMID: 36380037 Free PMC article. No abstract available.
Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors.
Xiao Z, Todd L, Huang L, Noguera-Ortega E, Lu Z, Huang L, Kopp M, Li Y, Pattada N, Zhong W, Guo W, Scholler J, Liousia M, Assenmacher CA, June CH, Albelda SM, Puré E. Xiao Z, et al. Among authors: scholler j. bioRxiv [Preprint]. 2023 Aug 7:2023.04.13.536777. doi: 10.1101/2023.04.13.536777. bioRxiv. 2023. Update in: Nat Commun. 2023 Aug 22;14(1):5110. doi: 10.1038/s41467-023-40850-5. PMID: 37090547 Free PMC article. Updated. Preprint.
Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α.
Roselle C, Horikawa I, Chen L, Kelly AR, Gonzales D, Da T, Wellhausen N, Rommel PC, Baker D, Suhoski M, Scholler J, O'Connor RS, Young RM, Harris CC, June CH. Roselle C, et al. Among authors: scholler j. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2317735121. doi: 10.1073/pnas.2317735121. Epub 2024 Feb 26. Proc Natl Acad Sci U S A. 2024. PMID: 38408246 Free PMC article.
Modulation of the gut microbiota engages antigen cross-presentation to enhance antitumor effects of CAR T cell immunotherapy.
Uribe-Herranz M, Beghi S, Ruella M, Parvathaneni K, Salaris S, Kostopoulos N, George SS, Pierini S, Krimitza E, Costabile F, Ghilardi G, Amelsberg KV, Lee YG, Pajarillo R, Markmann C, McGettigan-Croce B, Agarwal D, Frey N, Lacey SF, Scholler J, Gabunia K, Wu G, Chong E, Porter DL, June CH, Schuster SJ, Bhoj V, Facciabene A. Uribe-Herranz M, et al. Among authors: scholler j. Mol Ther. 2023 Mar 1;31(3):686-700. doi: 10.1016/j.ymthe.2023.01.012. Epub 2023 Jan 14. Mol Ther. 2023. PMID: 36641624 Free PMC article.
164 results