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Page 1
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL.
Eken JA, Koning MT, Kupcova K, Sepúlveda Yáñez JH, de Groen RAL, Quinten E, Janssen J, van Bergen CAM, Vermaat JSP, Cleven A, Navarrete MA, Ylstra B, de Jong D, Havranek O, Jumaa H, Veelken H. Eken JA, et al. Among authors: koning mt. J Exp Med. 2024 May 6;221(5):e20230941. doi: 10.1084/jem.20230941. Epub 2024 Mar 21. J Exp Med. 2024. PMID: 38512136 Free PMC article.
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia.
Quinten E, Sepúlveda-Yáñez JH, Koning MT, Eken JA, Pfeifer D, Nteleah V, De Groen RAL, Saravia DA, Knijnenburg J, Stuivenberg-Bleijswijk HE, Pantic M, Agathangelidis A, Keppler-Hafkemeyer A, Van Bergen CAM, Uribe-Paredes R, Stamatopoulos K, Vermaat JSP, Zirlik K, Navarrete MA, Jumaa H, Veelken H. Quinten E, et al. Among authors: koning mt. Haematologica. 2024 Mar 1;109(3):824-834. doi: 10.3324/haematol.2022.282542. Haematologica. 2024. PMID: 37439337 Free PMC article.
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
Maity PC, Bilal M, Koning MT, Young M, van Bergen CAM, Renna V, Nicolò A, Datta M, Gentner-Göbel E, Barendse RS, Somers SF, de Groen RAL, Vermaat JSP, Steinbrecher D, Schneider C, Tausch E, Bittolo T, Bomben R, Mazzarello AN, Del Poeta G, Kroes WGM, van Wezel JT, Imkeller K, Busse CE, Degano M, Bakchoul T, Schulz AR, Mei H, Ghia P, Kotta K, Stamatopoulos K, Wardemann H, Zucchetto A, Chiorazzi N, Gattei V, Stilgenbauer S, Veelken H, Jumaa H. Maity PC, et al. Among authors: koning mt. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4320-4327. doi: 10.1073/pnas.1913810117. Epub 2020 Feb 11. Proc Natl Acad Sci U S A. 2020. PMID: 32047037 Free PMC article.
Tandem Substitutions in Somatic Hypermutation.
Sepúlveda-Yáñez JH, Alvarez Saravia D, Pilzecker B, van Schouwenburg PA, van den Burg M, Veelken H, Navarrete MA, Jacobs H, Koning MT. Sepúlveda-Yáñez JH, et al. Among authors: koning mt. Front Immunol. 2022 Jan 7;12:807015. doi: 10.3389/fimmu.2021.807015. eCollection 2021. Front Immunol. 2022. PMID: 35069591 Free PMC article.
Acquisition of a glycosylated B-cell receptor drives follicular lymphoma toward a dark zone phenotype.
van Bergen CAM, Kloet SL, Quinten E, Sepúlveda Yáñez JH, Menafra R, Griffioen M, Jansen PM, Koning MT, Knijnenburg J, Navarrete MA, Kiełbasa SM, Veelken H. van Bergen CAM, et al. Among authors: koning mt. Blood Adv. 2023 Oct 10;7(19):5812-5816. doi: 10.1182/bloodadvances.2023010725. Blood Adv. 2023. PMID: 37493974 Free PMC article. No abstract available.
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