Puszko AK - Search Results

1

Towards Improved Peptidic α-Ketoamide Inhibitors of the Plasmodial Subtilisin-Like SUB1: Exploration of N-Terminal Extensions and Cyclic Constraints.

Puszko AK, Batista FA, Ejjoummany A, Bouillon A, Maurel M, Adler P, Legru A, Martinez M, Ortega Varga L, Hadjadj M, Alzari PM, Blondel A, Haouz A, Barale JC, Hernandez JF. Puszko AK, et al. ChemMedChem. 2025 Jan 20:e202400924. doi: 10.1002/cmdc.202400924. Online ahead of print. ChemMedChem. 2025. PMID: 39832214

2

Stimuli-Responsive Oligourea Molecular Films.

Grempka A, Dziubak D, Puszko AK, Bachurska-Szpala P, Ivanov M, Vilarinho PM, Pulka-Ziach K, Sek S. Grempka A, et al. Among authors: puszko ak. ACS Appl Mater Interfaces. 2024 Jun 19;16(24):31817-31825. doi: 10.1021/acsami.4c04767. Epub 2024 Jun 7. ACS Appl Mater Interfaces. 2024. PMID: 38848259 Free PMC article.

3

Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.

Legru A, Batista FA, Puszko AK, Bouillon A, Maurel M, Martinez M, Ejjoummany A, Ortega Varga L, Adler P, Méchaly A, Hadjadj M, Sosnowski P, Hopfgartner G, Alzari PM, Blondel A, Haouz A, Barale JC, Hernandez JF. Legru A, et al. Among authors: puszko ak. Eur J Med Chem. 2024 Apr 5;269:116308. doi: 10.1016/j.ejmech.2024.116308. Epub 2024 Mar 11. Eur J Med Chem. 2024. PMID: 38503166

4

Structure-activity relationship studies and biological properties evaluation of peptidic NRP-1 ligands: Investigation of N-terminal cysteine importance.

Puszko AK, Sosnowski P, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Bioorg Med Chem. 2023 Oct 30;94:117482. doi: 10.1016/j.bmc.2023.117482. Epub 2023 Sep 22. Bioorg Med Chem. 2023. PMID: 37774449 Free article.

5

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma.

Dumond A, Brachet E, Durivault J, Vial V, Puszko AK, Lepelletier Y, Montemagno C, Pagnuzzi-Boncompagni M, Hermine O, Garbay C, Lagarde N, Montes M, Demange L, Grépin R, Pagès G. Dumond A, et al. Among authors: puszko ak. J Exp Clin Cancer Res. 2021 Jan 18;40(1):33. doi: 10.1186/s13046-021-01832-x. J Exp Clin Cancer Res. 2021. PMID: 33461580 Free PMC article.

6

Urea-Peptide Hybrids as VEGF-A₁₆₅/NRP-1 Complex Inhibitors with Improved Receptor Affinity and Biological Properties.

Puszko AK, Sosnowski P, Rignault-Bricard R, Hermine O, Hopfgartner G, Pułka-Ziach K, Lepelletier Y, Misicka A. Puszko AK, et al. Int J Mol Sci. 2020 Dec 23;22(1):72. doi: 10.3390/ijms22010072. Int J Mol Sci. 2020. PMID: 33374715 Free PMC article.

7

Does Cysteine Rule (CysR) Complete the CendR Principle? Increase in Affinity of Peptide Ligands for NRP-1 Through the Presence of N-Terminal Cysteine.

Puszko AK, Sosnowski P, Raynaud F, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Biomolecules. 2020 Mar 13;10(3):448. doi: 10.3390/biom10030448. Biomolecules. 2020. PMID: 32183142 Free PMC article.

8

Urea moiety as amide bond mimetic in peptide-like inhibitors of VEGF-A₁₆₅/NRP-1 complex.

Puszko AK, Sosnowski P, Pułka-Ziach K, Hermine O, Hopfgartner G, Lepelletier Y, Misicka A. Puszko AK, et al. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2493-2497. doi: 10.1016/j.bmcl.2019.07.016. Epub 2019 Jul 10. Bioorg Med Chem Lett. 2019. PMID: 31326342

9

Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165.

Fedorczyk B, Lipiński PFJ, Puszko AK, Tymecka D, Wilenska B, Dudka W, Perret GY, Wieczorek R, Misicka A. Fedorczyk B, et al. Among authors: puszko ak. Molecules. 2019 May 6;24(9):1756. doi: 10.3390/molecules24091756. Molecules. 2019. PMID: 31064153 Free PMC article.

10

Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method.

Puszko AK, Sosnowski P, Tymecka D, Raynaud F, Hermine O, Lepelletier Y, Misicka A. Puszko AK, et al. Medchemcomm. 2019 Jan 25;10(2):332-340. doi: 10.1039/c8md00537k. eCollection 2019 Feb 1. Medchemcomm. 2019. PMID: 30881620 Free PMC article.

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